{rfName}
Ne

Indexed in

License and use

Altmetrics

Analysis of institutional authors

Valverde EAuthorGarcía-Alix AAuthor

Share

March 9, 2022
Publications
>
Article
No

Neonatal arterial stroke location is associated with outcome at 2 years: a voxel-based lesion-symptom mapping study

Publicated to:Archives of Disease in Childhood-Fetal and Neonatal Edition. 107 (1): 45-50 - 2022-01-01 107(1), DOI: 10.1136/archdischild-2020-320400

Authors: Núñez C, Stephan-Otto C, Arca G, Agut T, Arnaez J, Cordeiro M, Benavente-Fernández I, Boronat N, Lubián-López SP, Valverde E, Hortigüela M, García-Alix A

Affiliations

Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Madrid, Spain. - Author
Departament de Neonatologia, Hospital Clínic, IDIBAPS, Barcelona, Spain. - Author
Departament de Psiquiatria, Institut d'Investigació Biomèdica-Sant Pau (IIB-Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. - Author
Departamento de Neonatología, Hospital Puerta del Mar, Cádiz, Spain. - Author
Departamento de Neonatología, Hospital Universitario de Burgos, Burgos, Spain. - Author
Departamento de Neonatología, Hospital Universitario La Paz, Madrid, Spain. - Author
Departamento de Neonatología, Hospital Universitario y Politécnico La Fe. Instituto de Investigación Sanitaria La Fe, Valencia, Spain. - Author
Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain. - Author
Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain alfredoalix@gmail.com cstephanotto@pssjd.org. - Author
Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain. - Author
NeNe Foundation, Madrid, Spain alfredoalix@gmail.com cstephanotto@pssjd.org. - Author
NeNe Foundation, Madrid, Spain. - Author
Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain. - Author
See more

Abstract

In contrast to motor impairments, the association between lesion location and cognitive or language deficits in patients with neonatal arterial ischaemic stroke remains largely unknown. We conducted a voxel-based lesion-symptom mapping cross-sectional study aiming to reveal neonatal arterial stroke location correlates of language, motor and cognitive outcomes at 2 years of age.Prospective observational multicentre study.Six paediatric university hospitals in Spain.We included 53 patients who had a neonatal arterial ischaemic stroke with neonatal MRI and who were followed up till 2 years of age.We analysed five dichotomous clinical variables: speech therapy (defined as the need for speech therapy as established by therapists), gross motor function impairment, and the language, motor and cognitive Bayley scales. All the analyses were controlled for total lesion volume.We found that three of the clinical variables analysed significantly correlated with neonatal stroke location. Speech therapy was associated with lesions located mainly at the left supramarginal gyrus (p=0.007), gross motor function impairment correlated with lesions at the left external capsule (p=0.044) and cognitive impairment was associated with frontal lesions, particularly located at the left inferior and middle frontal gyri (p=0.012).The identification of these susceptible brain areas will allow for more precise prediction of neurological impairments on the basis of neonatal brain MRI.© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.

Keywords

NeonatologyNeurology

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Archives of Disease in Childhood-Fetal and Neonatal Edition due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2022, it was in position 13/130, thus managing to position itself as a Q1 (Primer Cuartil), in the category Pediatrics. Notably, the journal is positioned above the 90th percentile.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 2.6. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 1.14 (source consulted: FECYT Feb 2024)
  • Field Citation Ratio (FCR) from Dimensions: 2.91 (source consulted: Dimensions Jul 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-07-04, the following number of citations:

  • WoS: 5
  • Scopus: 5
  • Europe PMC: 2

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-07-04:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 47.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 47 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 4.
  • The number of mentions on the social network X (formerly Twitter): 7 (Altmetric).

Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: Last Author (GARCIA-ALIX PEREZ, ALFREDO).