{rfName}
Ch

Indexed in

License and use

Icono OpenAccess

Altmetrics

Grant support

This work was supported in part by CLARIFY project, within European Union's Horizon 2020 Research and Innovation Programme under grant agreement No. 875160, Instituto de Fomento de la Region de Murcia (INFO) and the European Regional Development Fund (FEDER).

Analysis of institutional authors

Provencio, MAuthorFranco, FAuthor

Share

February 17, 2022
Publications
>
Review

Chronodisruption and Ambulatory Circadian Monitoring in Cancer Patients: Beyond the Body Clock

Publicated to:Current Oncology Reports. 24 (2): 135-149 - 2022-02-01 24(2), DOI: 10.1007/s11912-021-01158-z

Authors: Almaida-Pagan, Pedro F.; Torrente, Maria; Campos, Manuel; Provencio, Mariano; Antonio Madrid, Juan; Franco, Fabio; Rodriguez Morilla, Beatriz; Cantos, Blanca; Sousa, Pedro A.; Martinez Madrid, Maria Jose; Pimentao, Joao; Angeles Rol, Maria;

Affiliations

Francisco de Vitoria Univ, Fac Hlth Sci, Madrid, Spain - Author
Hosp Univ Puerta Hierro Majadahonda, Serv Oncol Med, Madrid, Spain - Author
Inst Salud Carlos III, Ciber Fragilidad & Envejecimiento Saludable CIBER, Madrid, Spain - Author
Kronohlth SL, Murcia, Spain - Author
Puerta Hierro Majadahonda Univ Hosp, Med Oncol Dept, Calle Manuel de Falla 1, Madrid 28222, Spain - Author
Univ Murcia, Coll Biol, Dept Physiol, IUIE,IMIB Arrixaca,Chronobiol Lab, Mare Nostrum Campus, Murcia, Spain - Author
Univ Nova Lisboa, Fac Sci & Technol, Dept Elect Engn, Lisbon, Portugal - Author
See more

Abstract

Purpose of Review Circadian rhythms impose daily rhythms a remarkable variety of metabolic and physiological functions, such as cell proliferation, inflammation, and DNA damage response. Accumulating epidemiological and genetic evidence indicates that circadian rhythms' disruption may be linked to cancer. The integration of circadian biology into cancer research may offer new options for increasing cancer treatment effectiveness and would encompass the prevention, diagnosis, and treatment of this disease.Recent Findings In recent years, there has been a significant development and use of multi-modal sensors to monitor physical activity, sleep, and circadian rhythms, allowing, for the very first time, scaling accurate sleep monitoring to epidemiological research linking sleep patterns to disease, and wellness applications providing new potential applications.Summary This review highlights the role of circadian clock in tumorigenesis, cancer hallmarks and introduces the stateof-the-art in sleep-monitoring technologies, discussing the eventual application of insights in clinical settings and cancer research.

Keywords

ambulatory circadian monitoringcancer patientschronodisruptioncircadian rhythmsmulti-modal sensorsAmbulatory circadian monitoringBreast-cancerCancer patientsChronodisruptionCircadian rhythmsDiurnal cortisol rhythmLung-cancerMotor-activityMulti-modal sensorsPatients receiving treatmentQuality-of-lifeRest-activity rhythmSleep disturbancesSurface-temperature rhythmsTumorigenesisWrist temperature

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Current Oncology Reports due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2022, it was in position , thus managing to position itself as a Q1 (Primer Cuartil), in the category Oncology.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 1.35. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 1.18 (source consulted: FECYT Feb 2024)
  • Field Citation Ratio (FCR) from Dimensions: 3.26 (source consulted: Dimensions Jul 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-07-18, the following number of citations:

  • WoS: 6
  • Scopus: 6
  • Europe PMC: 5

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-07-18:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 21.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 37 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.5.
  • The number of mentions on the social network X (formerly Twitter): 2 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
  • Assignment of a Handle/URN as an identifier within the deposit in the Institutional Repository: https://repositorio.uam.es/handle/10486/706146

Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Portugal.