{rfName}
An

Indexed in

License and use

Citations

11

Altmetrics

Analysis of institutional authors

Martin Ventura, Jose LuisAuthor

Share

Publications
>
Article

Anexinas: implicación en la homeostasis del colesterol, la respuesta inflamatoria y la aterosclerosis

Publicated to:Clinica e Investigacion en Arteriosclerosis. 33 (4): 206-216 - 2021-01-01 33(4), DOI: https://doi.org/10.1016/j.arteri.2020.12.010

Authors: Méndez Barbero, Nerea; Gutiérrez Muñoz, Carmen; Blázquez Serra, Rafael; Martín Ventura, José Luis; Blanco Colio, Luis Miguel

Affiliations

Abstract

The annexin superfamily consists of 12 proteins with a highly structural homology that binds to phospholipids depending on the availability of Ca2+-dependent. Different studies of overexpression, inhibition, or using recombinant proteins have linked the main function of these proteins to their dynamic and reversible binding to membranes. Annexins are found in multiple cellular compartments, regulating different functions, such as membrane trafficking, anchoring to the cell cytoskeleton, ion channel regulation, as well as pro- or anti-inflammatory and anticoagulant activities. The use of animals deficient in any of these annexins has established their possible functions in vivo, demonstrating that annexins can participate in relevant functions independent of Ca2+ signalling. This review will focus mainly on the role of different annexins in the pathological vascular remodelling that underlies the formation of the atherosclerotic lesion, as well as in the control of cholesterol homeostasis.Copyright © 2021 Sociedad Española de Arteriosclerosis. Publicado por Elsevier España, S.L.U. All rights reserved.

Keywords

anexinasannexinsaterosclerosisatherosclerosischolesterolcolesterolinflamaciónInflammation

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Clinica e Investigacion en Arteriosclerosis, Q3 Agency Scopus (SJR), its regional focus and specialization in Cardiology and Cardiovascular Medicine, give it significant recognition in a specific niche of scientific knowledge at an international level.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2025-05-29:

  • Scopus: 11

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-05-29:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 22 (PlumX).