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Analysis of institutional authors

Cuarental LAuthorVanessa Perez-Gomez, MariaCorresponding AuthorOrtiz, AlbertoCorresponding AuthorFernandez-Fernandez, BeatrizCorresponding AuthorSanchez-Nino MdAuthor

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Phosphate, microbiota and ckd

Publicated to:Nutrients. 13 (4): 1273- - 2021-04-01 13(4), DOI: 10.3390/nu13041273

Authors: Favero, Chiara; Carriazo, Sol; Cuarental, Leticia; Fernandez-Prado, Raul; Goma-Garces, Elena; Vanessa Perez-Gomez, Maria; Ortiz, Alberto; Fernandez-Fernandez, Beatriz; Dolores Sanchez-Nino, Maria

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Abstract

Phosphate is a key uremic toxin associated with adverse outcomes. As chronic kidney disease (CKD) progresses, the kidney capacity to excrete excess dietary phosphate decreases, triggering compensatory endocrine responses that drive CKD-mineral and bone disorder (CKD-MBD). Eventu-ally, hyperphosphatemia develops, and low phosphate diet and phosphate binders are prescribed. Recent data have identified a potential role of the gut microbiota in mineral bone disorders. Thus, parathyroid hormone (PTH) only caused bone loss in mice whose microbiota was enriched in the Th17 cell-inducing taxa segmented filamentous bacteria. Furthermore, the microbiota was required for PTH to stimulate bone formation and increase bone mass, and this was dependent on bacterial production of the short-chain fatty acid butyrate. We review current knowledge on the relationship between phosphate, microbiota and CKD-MBD. Topics include microbial bioactive compounds of special interest in CKD, the impact of dietary phosphate and phosphate binders on the gut microbiota, the modulation of CKD-MBD by the microbiota and the potential therapeutic use of microbiota to treat CKD-MBD through the clinical translation of concepts from other fields of science such as the optimization of phosphorus utilization and the use of phosphate-accumulating organisms.

Keywords

chronic kidney diseasemicrobiotaphosphatephosphate binderpthshort chain fatty acidAnimalsChelating agentsChronic kidney diseaseChronic kidney disease-mineral and bone disorderDisease models, animalDisease progressionGastrointestinal microbiomeHolistic healthHumansHyperphosphatemiaMiceMicrobiotaParathyroid hormonePhosphatePhosphate binderPhosphorus, dietaryProbioticsPthRenal insufficiency, chronicShort chain fatty acidTh17 cellsUremic toxins

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Nutrients due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2021, it was in position 15/90, thus managing to position itself as a Q1 (Primer Cuartil), in the category Nutrition & Dietetics.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 2.65. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 2.57 (source consulted: FECYT Feb 2024)
  • Field Citation Ratio (FCR) from Dimensions: 8.83 (source consulted: Dimensions Jun 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-06-08, the following number of citations:

  • WoS: 27
  • Scopus: 28
  • Europe PMC: 13
  • OpenCitations: 26

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-06-08:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 86.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 85 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.25.
  • The number of mentions on the social network X (formerly Twitter): 2 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
  • Assignment of a Handle/URN as an identifier within the deposit in the Institutional Repository: https://repositorio.uam.es/handle/10486/697605

Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Favero, Chiara) and Last Author (Dolores Sanchez-Nino, Maria).

the authors responsible for correspondence tasks have been Fernandez-Prado, Raul, PEREZ GOMEZ, MARIA VANESSA, ORTIZ ARDUAN, ALBERTO, FERNANDEZ FERNANDEZ, BEATRIZ and Dolores Sanchez-Nino, Maria.