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Analysis of institutional authors

Martinez‐fernandez LAuthor

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March 5, 2020
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Excited state dynamics of 8‐vinyldeoxyguanosine in aqueous solution studied by time‐resolved fluorescence spectroscopy and quantum mechanical calculations

Publicated to: MOLECULES. 25 (4): 824- - 2020-02-13 25(4), DOI: 10.3390/molecules25040824

Authors:

Martinez-Fernandez, L; Gustavsson, T; Diederichsen, U; Improta, R
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Affiliations

CNR, Ist Biostrutture & Bioimmagini, Via Mezzocannone 16 - Author
Istituto di Biostrutture e Bioimmagini - Author
Univ Autonoma Madrid, IADCHEM, Inst Adv Res Chem - Author
Univ Goettingen, Inst Organ & Biomol Chem, Tammannstr 2 - Author
Univ Paris Saclay, LIDYL, CNRS, CEA - Author
Universidad Autónoma de Madrid - Author
Universitat Gottingen - Author
Université Paris-Saclay - Author
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Abstract

© 2020 by the authors. The fluorescent base guanine analog, 8‐vinyl‐deoxyguanosine (8vdG), is studied in solution using a combination of optical spectroscopies, notably femtosecond fluorescence upconversion and quantum chemical calculations, based on time‐dependent density functional theory (TD‐DFT) and including solvent effect by using a mixed discrete‐continuum model. In all investigated solvents, the fluorescence is very long lived (3¥4 ns), emanating from a stable excited state minimum with pronounced intramolecular charge‐transfer character. The main non‐radiative decay channel features a sizeable energy barrier and it is affected by the polarity and the H‐bonding properties of the solvent. Calculations provide a picture of dynamical solvation effects fully consistent with the experimental results and show that the photophysical properties of 8vdG are modulated by the orientation of the vinyl group with respect to the purine ring, which in turn depends on the solvent. These findings may have importance for the understanding of the fluorescence properties of 8vdG when incorporated in a DNA helix.
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Keywords

dnafluorescent probetd-dftSolvent effect

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Molecules due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2020, it was in position , thus managing to position itself as a Q1 (Primer Cuartil), in the category Pharmaceutical Science.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-03-11:

  • WoS: 6
  • Scopus: 5
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-03-11:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 12 (PlumX).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
  • Assignment of a Handle/URN as an identifier within the deposit in the Institutional Repository: https://repositorio.uam.es/handle/10486/694544
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Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: France; Germany; Italy.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (MARTINEZ FERNANDEZ, LARA) .

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