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Analysis of institutional authors

Laclaustra MCorresponding AuthorLopez-Garcia EAuthorGarcía-Esquinas, EAuthorGraciani AAuthorGuallar-Castillon PAuthorBanegas JAuthorRodriguez-Artalejo FAuthor
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Article

LDL cholesterol rises with BMI only in lean individuals: Cross-sectional U.S. And Spanish representative data

Publicated to:DIABETES CARE. 41 (10): 2195-2201 - 2018-10-01 41(10), DOI: 10.2337/dc18-0372

Authors: Laclaustra, Martin; Lopez-Garcia, Esther; Civeira, Fernando; Garcia-Esquinas, Esther; Graciani, Auxiliadora; Guallar-Castillon, Pilar; Banegas, Jose R; Rodriguez-Artalejo, Fernando

Affiliations

Hospital Miguel Servet - Author
UAM, CSIC, Ctr Excelencia Int, Inst Madrileno Estudios Avanzados Alimentac IMDEA, Madrid, Spain - Author
Univ Autonoma Madrid, Inst Invest Hosp La Paz IDIPAZ, Ctr Invest Biomed Red Epidemiol & Salud Publ CIBE, Dept Prevent Med & Publ Hlth,Sch Med, Madrid, Spain - Author
Univ Zaragoza, Hosp Univ Miguel Servet, Ctr Invest Biomed Red Enfermedades Cardiovasc CIB, Zaragoza, Spain - Author
Univ Zaragoza, Hosp Univ Miguel Servet, Inst Invest Sanitaria Aragon IIS Aragon, Translat Res Unit, Zaragoza, Spain - Author
Universidad Autónoma de Madrid - Author
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Abstract

© 2018 by the American Diabetes Association. OBJECTIVE: Elevated LDL cholesterol (LDLc) is not strongly associated with obesity or metabolic syndrome (MS), but this relationship repeatedly has been examined assuming a linear association. This study aimed to assess the dose-response relationship between body mass index (BMI) or waist circumference (WC) and LDLc and to evaluate its link to metabolic impairment. RESEARCH DESIGN AND METHODS: Participants in the continuous National Health and Nutrition Examination Survey (NHANES, 1999-2010) (n = 12,383) and the Study on Nutrition and Cardiovascular Risk (ENRICA, 2008-2010) (n = 11,765), representative samples of U.S. and Spanish noninstitutionalized populations, were cross-sectionally investigated. LDLc was modeled with age- and sex-adjusted regressions, with BMI and/or WC as explanatory variables included in models as two-segment linear and natural cubic splines. RESULTS: In NHANES and ENRICA, slopes of the BMI-LDLc association changed (P < 0.001) at BMI 27.1 and 26.5 kg/m2, respectively, forming an inverted U shape. Below these BMI inflection points, LDLc rose 2.30 and 2.41 mg/dL per kg/m2 (both P < 0.001). However, above said points, LDLc declined 20.37 and 20.38 mg/dL per kg/m2 (both P < 0.001). The WC-LDLc relationship was similar to the BMI-LDLc relationship. Accumulation of MS traits was associated with a weakening of the positive BMI-LDLc association among lean participants (below the BMI inflection point). Aging shifted the inflection point of the BMI-LDLc relationship to lower BMI values. CONCLUSIONS: The BMI- and WC-LDLc relationships have inverted U shapes. Diminishing associations between BMI and LDLc might indicate metabolic impairment as a result of aging or other metabolic diseases. In lean individuals, small weight losses might help to lower LDLc for cardiovascular prevention.

Keywords
Advanced and specialized nursingAntropologia / arqueologiaBiotecnologíaCiências biológicas iCiências biológicas iiEndocrinology & metabolismEndocrinology, diabetes and metabolismEnfermagemEngenharias ivGeneral medicineInterdisciplinarInternal medicineMedicina iMedicina iiMedicina iiiNutriçãoOdontologíaSaúde coletiva

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal DIABETES CARE due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2018, it was in position 4/144, thus managing to position itself as a Q1 (Primer Cuartil), in the category Endocrinology & Metabolism. Notably, the journal is positioned above the 90th percentile.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 1.38. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 1.83 (source consulted: FECYT Feb 2024)
  • Field Citation Ratio (FCR) from Dimensions: 8.14 (source consulted: Dimensions May 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-05-16, the following number of citations:

  • WoS: 34
  • Scopus: 37
  • Europe PMC: 3
  • Google Scholar: 57
  • Open Alex: 45
  • OpenCitations: 38
Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-05-16:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 91.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 91 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 21.93.
  • The number of mentions on the social network Facebook: 1 (Altmetric).
  • The number of mentions on the social network X (formerly Twitter): 13 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (LACLAUSTRA GIMENO, MARTÍN) and Last Author (RODRIGUEZ ARTALEJO, FERNANDO).

the author responsible for correspondence tasks has been LACLAUSTRA GIMENO, MARTÍN.