I achieved my bachelor's degree in Biological Sciences thesis and my PhD in Sciences  at Universidad Autónoma de Madrid, under the supervision of Dr. Rosario Perona. Afterwards, I performed two postdoctoral stays: First at Dr. Rosario Perona´s lab, second in London (UK) at the Cancer Research UK (Sir. Dr. Paul Nurse Lab) and at NIMR (MRC; Dr. J. Millar Lab). For funding these stays, I was awarded with a competitive scholarships from MEC-FPU grant, a postdoctoral Comunidad de Madrid grant, and later on with a contract as MIMR research Staff (2003-2005). I joined the Biochemistry Department (UAM) thanks to a Ramón y Cajal grant. I was next permanently appointed as Profesor Contratado Doctor (PCD) at UAM, where I currently serve as Profesor Titular at the Department of Biochemisty of the Faculty of Medicine. I have also been dedicated to academic management and institutional responsibilities, as the Academic Secretary of the Biochemistry Department, the Coordinator of the PhD Programme in Molecular Biosciences with an Award towards Excellence  and later as the Academic Register of the Faculty of Medicine.

My research lines have focused on the physiopathology and biochemistry of cancer. During the predoctoral period, I studied the molecular mechanisms by which cisplatin (an anticancer drug with a wide clinical use) induces cell death. I identified the JNK/DUSP1 stress signalling pathway as cisplatin key modulators for apoptosis induction (DOI:10.1038/sj.onc.120157; 10.1038/sj.onc.1203887) (10.1091/mbc.E02-01-0022 ). In addition, I identified genes responsible for cisplatin sensitivity (DOI: 10.1182/blood-2007-04-083261). These last results were the basis of a patent PCT/ES2006/070152 currently in exploitation that was awarded with Madrid+d 2012 Accésits. In addition, the associated publication has been cited in different patents. Another reseach milestone was the identification in S. pombe a new complex of proteins that causes aneuploidy  (10.1038/sj.emboj.7600761). Since 2005 I lead the Chromosomal instability and Therapy response research group at UAM, thanks to the obtention of public grants ISCIII (4) and MINECO (1). The main interest of our group is to identify biomarkers for diagnosis and to unveil the metallo-drugs responses in gastric cancer (GC). Some important contributions to the field are a) identification of Chk1 as biomarker resistance (10.1038/srep21519), b) the role of MAD2 in GC tumorigenesis (10.4161/15384101.2014.962952) DOI:10.7150/thno.49270) in collaboration with Dr. Sainz (IIBm) and Dr. Foijer (ERIBA), c) the role of NER repair pathway as potential targets for improved response to cisplatin treatment. (10.3389/fphar.2019.00377).d) the role senescence induction by drugs and it relationship with therapy response. doi.org/10.4161/15384101.2014I e) new potential metallodrugs for cancer treatment. 10.1021/acsomega.9b02831 More recently, I have participated as the research coordinator of the Biochemistry/Molecular Biology team in a collaborative project granted by Comunidad de Madrid with European Funds (REACT-EU) dedicated to understanding the tissular impact of SARS-CoV2 (2020-2022). Other collaboration Dr. SanchezPrieto (UCLM- CSIC)), Dr. Varela (CSIC), Dr. Peiró (UAM) Dr. Perona R (CSIC), and Dr. Bruno Sainz, Jr

I am currently a member of  IRYCIS Cancer stem cells and fibroinflammatory microenvironment and CIBERER Member Cáncer Hereditario y Síndromes Relacionados. I am the co-author of 50 publications in scientific journals indexed in the JCR and have acted as a  manuscript reviewer for a large number of journals, including Scientific Reports, Cancer letters, Oncotarget, FEBS Open Bio, BMC Cancer, Biomed Research International. As a grant evaluator, I collaborate with ANEP and ACSUCYL, AGAE, CAIXA, and ISCIII. President of the technical committee of  Human Resourcer for ISCIII, since 2019.

I would highlight that thanks to my research and academic expertise I have been able to provide valuable tools and trained my PhD students to obtain an excellent grade of formation, including the International Mention in their doctoral thesis . I have supervised 4 doctoral students who are now enrolled either in academia or in private companies. Regarding human resources, I have obtained and backed the obtention of competitive grants such as predoctoral FPU and FPI-UAM, Ayudante de Investigacion (CAM), Investigo (CAM) and Tecnico de Laboratorio (CAM) in Comunidad de Madrid convocatorias,  which are essential for the success of a research team.

As an academic researcher, I have supervised more than 10 Final Degree (TFG) and Master (TFM) theses. Furthermore, I have organized events and official PhD training activities according with EURODOC guidelines (www.eurodoc.net) related to transversal skills. Some examples are the academic direction of symposium and communication courses at UAM, the Facilitating Leadership in a Knowledge-Based Society held at Harvard University (IAP-UAM) or the  participation in the CIVIS European Alliance Summer School The Challenged of Aging. Moreover, I have contributed to the dissemination of science to society, by participating in two FECYT projects: Escape Room with Science. Campus Científicos de Verano 2019 and in two European Researchers' Nights 2016 and 2019