The Collegium Beatus Rhenanus (CBR) is a structure of research and higher education, established in 1997, concerning the Sciences of Antiquity. Named after the humanist Beatus Rhenanus (1485-1547), symbol of the intellectual unity of the region. In fact, the curriculum of the CBR is heir to the humanist tradition of the Upper Rhine, bringing together the specific and scientific skills and expertise of two French Universities (Strasbourg and Mulhouse), one German (Freiburg) and another Swiss (Basel). Our aim purpose is to study how inter-university collaboration is set and planned between research groups from three different nations, by means of fruitful exchange of information. We will also analyze how the support for the implementation of joint research projects is established and how the maximum dissemination of scientific results is guaranteed. Our approach starts considering the programme for training young researchers, examining the educational guides of the disciplines of History and Science of Antiquity area as well as the Proceedings of the annual meetings of the CBR, in order to assess the impact of the intertwining of multiple and diverse university traditions.