Indexado en

Licencia y uso

Citaciones

Cited 1 times in

Cited 109 times in

Altmetrics

Grant support

The EAGLE study was funded by the ESCP. Ethicon provided an unrestricted educational grant to the ESCP which was used in supporting the development of the online education materials. The NIHR Global Health Research Unit on Global Surgery (NIHR133364) provided support, notably in accessing and supporting collaborating teams in low-and middle-income countries. The funders had no role in the design, set-up, running or analysis of this study, or writing of this report. The views expressed are those of the authors and not necessarily those of the ESCP, Ethicon, or NIHR.

Análisis de autorías institucional

Compartir

Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries

Publicado en:BRITISH JOURNAL OF SURGERY 111 (1): znad370- - 2023-11-29 111(1), DOI: 10.1093/bjs/znad370

Autores: Li, Elizabeth; Bengueddach, A; Tidjane, A; Tabeti, B; Behilil, C; Boudjenan-Serradj, N; Bensafir, S; Meharzi, S E, I; Aissat, A; Ghouali, A K; Larabi, K; Riffi, O; Kacimi, S E O; Mesli, S N; Rezoug, W; Mitidieri, A; Jose, A; Pablo, C; Rodriguez, C A; Panettiere, M F; Barbalace, N; Juan, T; Lucena, J; Houdin, A; Fernandez, E; Lococo, J; Pedro, L; Loban, M; Vecchio, P; Grinblat, A; Carrie, A; Veracierto, F; Santillan, M; Napolitano, M; Avellaneda, N; La Rosa, S; Gonzalez, C M; Ferro, E; Munoz, J P; Ventorutti, T; Cabrera, C; Carrizo, C; Mospane, C; Leiro, F; Espino, J; Trama, M; Bianchi, R; Potolicchio, A; Dindri, F; Buey, L; Lucas, N; Catalano, P; Astilleta, R; Quiroga, Y; Chwat, C; Valli, D; Alexandre, F; Martres, G; Rosato, G; Lemme, G; Romero, V; Doniquian, A M; Pachajoa, D A Pantoja; Llahi, F; Fiorenza, J M; Parodi, M; Ocana, N; Gallardo, A; Valenzuela, A; Perriello, J; Nador, R; Fermani, C; Garay, L; Blanco, P; Villalobos, S; Posner, F; Vieyra, N; Fiorito, P; Ciabattari, P; de Kort, C; Daryanani, D; Smit, J; Gosselink, M P; Janssen, N; Feiss, A; Lee, C H A; Taylor, D; Edington, J; Chen, N; Ong, W M; Aigner, F; Moitzi, G; Gemes, G; Braumille, M; Mitteregger, M; Gerald, S; Uranitsch, S; Belarmino, A; Waha, J; Kahn, J; Treiber, M; Schemmer, P; Mikalauskas, S; Ibrahimli, A; Samadov, E; Orujova, E; Namazov, I; Alikhanli, J; Asgarov, M; Kutkut, A; Almahmeed, E; Aljawder, H; Juma, I; Johnston, K; Saeed, M F; Khairi, S; Matovic, E; Omerasevic, M; Delibegovic, S; Hodzic, S; Rudell, A G; Fuzari, J; Farah, J F; Nadal, L R M; Dos Santos, M B A; Lupinacci, R A; Pereira, T S; Sete, A da Silveira; Filho, A Lacerda; Pires, B L de Souza; de Queiroz, F Lopes; Amaral, H A T; Dos Santos, M A M; Silvestre, S C de Miranda; Hanan, B; Reis, C; Cassia, G; da Luz, M; Delgado, M; Campanati, R; Silva, R; Bomfa-Barbosa, A; Alves, B C; Costa, B X M; Cortes, B G Werneck; Lemos, F H T; Arreguy-Borges, K; Silva, T Barbosa; Assis, A; Freitas, A H; Rezende, D; Silva, H; Alvarenga, I; Cascais, R; Silva, T; Santos, G; Pinto, H; Silva, I; Leite, L; Massahud, M; Meyer, M; Tiburcio, R; Martinez, C A R; Espinha, D R; Marson, F A L; Goes, I A de Oliveira; Artioli, L M de Souza; Boschiero, M N; Takahashi, C Y; de Oliveira, F G; Junior, H F Lyra; de Oliveira, J C C; Dos Santos, J M; Gerber, M T; Erdmann, T R; Barbosa, A; Fernandes, A; Junior, A Nasser; Junior, H Moreira; Moreira, J; Ribeiro, M; Moreira, P; Carvalho, A; Santos, B; Fidelis, F; Cruz, I; Codes, L; Aibe, R; Boudoux, S; Favacho, B C; Pinto, F; Gava, G; Pivati, I R; Vilain, L F; Kim, N; Nunes, R Leite; Dimitrov, D; Peneva, K; Karamanliev, M; Dimitrova, S; Ivanov, T; Atanasov, B; Dzharov, G; Shtereva, M; Slavchev, M; Belev, N; Krastev, P; Arabadzhiev, A; Tonova, D; Tzoneva, D; Sokolov, M; Gribnev, P; Maslyankov, S; Pavlov, V; Bakmaz, B; Dijan, E; Coza, I; Mihanovic, J; Kucic, J; Sulen, N; Katusic, Z; Hudacek, K; Farkasova, M; Markova, M; Grolich, T; Kala, Z; Pazdirek, F; Hoch, J; Filipova, L; Kocian, P; Prikryl, P; Hogn, A; Moller, B; Slot, D K; Baelum, J K; La Cour, K; Ellebaek, M B; Eriksen, N D; Mahmoud, A; Abdellatif, A; Nafea, A; Ewedah, M; Soliman, M; Yakout, N; Argawy, O; Sallam, I; Kamel, I; Sherif, M; Ashmawy, S; Ali, A; Saad, M; Ahmed, M; Mohamed, M; Mohamed, N; Mahmoud, S; Rashed, A M; Abd-Errazik, M A; Ammar, M A; Mohammed, R; Ebrahem, A; El Aal, A A; Abdou, K; Wagdy, M; Qassem, M; Taha, M; Shehta, A; El Metwally, A; Hamed, H; Ali, M A; Elrefai, M; El Sorogy, M; Abdelkhalek, M; Ragab, A; Refky, B; Metwally, I H; Kamal, M; Zuhdy, M; Shetiwy, M; Sakr, A; Elfallal, A; Elfeki, H; Eldakroury, I; Elbahrawy, K; Mostafa, M; Emile, S; Tessema, A; Tasew, A; Gezahegn, H; Bekele, K; Belay, M; Gudisa, Z; Teferu, Z; Vayrynen, A; Kechagias, A; Turunen, A; Katunin, J; Parhiala, M; Pengerma, P; Lahti, P; Carpelan, A; Vihervaara, H; Huhtinen, H; Pasonen, J; Heino, R; Pakarinen, S; Falenius, V; Pinard, B; Nobile, C; Duchalais, E; Drissi, F; Meurette, G; Podevin, J; Lepenndu, M; Hoetzel, A; Jud, A; Jauch, D; Stefan, F-F; Neeff, H; Holzner, P; Nguyen, P; Ryl, A; Kehl, F; Pullig, F; Baral, J; Munch, S; Futterer, C; Reissfelder, C; Sandra-Petrescu, F; Herrle, F; Hardt, J; Lamm, L; Seyfried, S; Gharbi, A; Aydin, F; Stavrou, G; Sperber, J; de Deken, J; Schwarzkopf, K; Widyaningsih, R; Polidorou, A; Mpakas, A; Tokidis, E; Loun, L; Petropoulou, T; Balalis, D; Korkolis, D; Manatakis, D; Assimakopoulou, E; Bourazani, M; Gklavas, A; Kalamara, E; Papaconstantinou, I; Theodoraki, K; Chardalias, L; Konstadoulakis, M; Theodosopoulos, T; Soulioti, E; Kavezou, F; Filippou, J; Papadoliopoulou, M; Michalopoulos, N; Vassiliu, P; Sidiropoulos, T; Charakopoulou, A; Panagiotou, A; Bouchagier, K; Kokkinakis, K; Lambridi, E; Psarologos, M; Sotiropoulou, M; Giannaraki, S; Kapiris, S; Triantafyllou, A; Theodoropoulos, C; Matthaiou, G; Westzaan, N; Etelka, S; Triantafyllou, T; Theodoropoulos, G; Schizas, D; Mpaili, E; Karydakis, L; Mpoura, M; Danassi, D; Karavokyros, I; Dimitriou, N; Livanou, X; Kikira, A; Tsourouflis, G; Tomara, N-K; Nikiteas, N; Dorovinis, P; Garoufalia, Z; Tsiotos, G; Stamou, K; Kocka, N; Ballian, N; Kalakonas, S; Athanasakis, E; Chrysos, E; Xynos, E; Tsiaoussis, J; Papadaki, K; Xenaki, S; Nyktari, V; Sarakatsianou, C; Bompou, E; Arnaoutoglou, E; Tzovaras, G; Baloyiannis, I; Mamaloudis, I; Perivoliotis, K; Apostolidi, E; Mulita, F; Karpetas, G; Maroulis, I; Vailas, M; Petra, A; Kontis, E; Kaouras, E; Katsaros, I; Katsiaras, L; Manikis, P; Papadopoulou, T; Papadopoulos, A; Manioti, E; Zeringa, G; Katsinelis, I; Mouzakis, O; Kouki, P; Nikolaou, V; Marinis, A; Alexopoulou, K; Papadaki, M; Vederaki, S-A; Samara, A; Giakoustidis, D; Christodoulidis, G; Bareka, M; Chatzikomnitsa, P; Tsigara, S; Papadopoulos, V; Zarzava, E; Anestiadou, E; Lydia, L; Apostolakidou, M; Ioannidis, O; Simeonidis, S; Mpitsianis, S; Futaba, K; Tam, P T H; Ng, S S M; Lau, V N M; Tse, W K; Banky, B; Dolhai, E; Golub, J; Marton, J; Lakatos, L; Susztak, N; Maurya, A P; Kumawat, H; Saxena, P; Lather, R; Waindeskar, V; Khanduri, A; Goyal, L; Gupta, R; Singh, S; Saksena, A R; Rayani, B K; Kasula, J; Raju, K; Shah, M M; Thammineedi, S R; Patnaik, S C; Rathod, D; Poonia, D R; Vishnoi, J R; Sharma, N; Byshetty, R; Yadav, R K; Misra, S; Dhali, A; Dhali, G K; Biswas, J; Ray, S; Ghose, T; Pipara, A; Singh, H M; Roy, M K; Desai, N; Thambudorai, R; Ishwarappagol, V; Chaturvedi, A; Verma, D; Akhtar, N; Gupta, S; Rajan, S; Tiwari, T; Kumar, V; Mahajan, A; Jain, D; Liddle, D; Jyoti, J; Haque, P D; Jain, R; Veetil, S K; Prem, W; Lakshminarayana, B; Veerabhadrappa, B S; Poojary, P H; Bhat, R R Krishna; Mathew, S; Gupta, L; Bains, L H; Bains, L; Kumar, M; Singh, N; Lal, P; Sharma, A; Kumar, A; Garg, L; Aggarwal, M; Jakhar, R; Bose, B; Huda, F; Thakur, N; Dhar, P; Seenivasagam, R Kottayasamy; Prakash, S; Chaudhari, A; Shukla, A; Mahakalkar, C; Saxena, G; Mahuli, K; Kaple, M; Kshirsagar, S; Mehraj, A; Parray, F; Aziz, G; Chowdri, N; Wani, R F; Gurcoo, S; Shah, Z; Polamreddy, B M; Madhavan, S; Subbarayan, S; Vino, S; Aravindan, U; George, G; Harikumar, C K; Yadev, I P; Chisthi, M; Revathy, P S; Sreekumar, R C; Vijayan, V; Theodore, B; Victor, C; Jesudason, M R; Arulappan, N; Philip, R; Mittal, R; Durai, S; Creavin, B; Cullinane, C; Davis, C; Flynn, C; Liam, D; Cooke, F; Earley, H; Mccullough, P; Neary, P; Hamilton, V; Di Trani, A; Conversano, I; Cianci, P; Petta, R; Picciariello, A; Altomare, D F; Martines, G; Grasso, S; Moffa, S; Papagni, V; Zanoni, A; Belvedere, A; Gori, A; Romano, A; Cuicchi, D; Di Croce, G; Tanzanu, M; Rottoli, M; Cardelli, S; Lauro, A; Sartarelli, L; Binetti, M; Cervellera, M; Tonini, V; Sanna, B; Pusceddu, E; Runfola, M; Manunza, R; Pisanu, A; Cois, A; Frongia, F; Esposito, G; Podda, M; Mura, P; Marzella, A; Scotto, B; Cuneo, D; Ascari, F; Giulino, G; Varoli, M; Laquatra, N; Fortunato, C; Marino, F; Perrone, F; Pace, M; Convertini, O; Cutelle, C; Ammerata, G; Sena, G; Pignataro, M; Scozzafava, M; Mazza, M; Bruni, A; Curro, G; Hila, J; Ammendola, M; Curcio, S; Signorelli, V; Marano, A; Sasia, D; Borghi, F; Giuffrida, M Carmela; Bonardello, M; Palmisano, S; Testa, V; Porta, A; Scaltrini, F; Iacob, G; Gaspa, I; Guatteri, L; Coladonato, M; Zapparoli, A; Pesce, A; Feo, C, V; Pindozzi, F; Bigoni, I; Torchiaro, M; Fabbri, N; Cianchi, F; Staderini, F; Elena, F; Coratti, F; Barbato, G; Fortuna, L; Romagnoli, S; Bergamini, C; Villa, G; Cecchini, I; Martellucci, J; Izzo, M; Trafeli, M; Scheiterle, M; Manoocheehri, F; Cagnazzo, F; Spampinato, M G; Adam, N; Depalma, N; D'Ugo, S; Garritano, S; Mazzeo, C; Cucinotta, E; Melita, F; Viscosi, F; Fleres, F; Biondo, S A; Tripodi, V F; Spinelli, A; Foppa, C; Greco, M; Sacchi, M; Carvello, M; Deac, V; Laurenti, V; Frontali, A; Zappone, A; Cammarata, F; Colombo, F; Ferrario, L; Curra, M C; Danelli, P; Vignali, A; Umberto, C; Mastriale, F; Riccardo, R; Turi, S; Elmore, U; Galimberti, A; Ceretti, A Pisani; Vespo, D; Opocher, E; Longhi, M; Mariani, N M; Flandoli, C; Ciulli, C; Vaira, G; Ripamonti, L; Cigagna, L; Oldani, M; Tamini, N; Palumbo, A; Castaldi, A; Antropoli, C; Rupealta, N; Palmiero, N; Donatiello, V; Novi, A; Cappiello, A; Bianco, F; de Luca, M; Incollingo, P; Esposito, R; Gili, S; Aprea, G; de Simone, G; Palomba, G; Capuano, M; Basile, R; D'Angelo, S; Tropeano, F P; Luglio, G; Pagano, G; de Palma, G D; Cricri, M; Milone, M; Manigrasso, M E; Anoldo, P; Boccia, G; Raiano, G; Di Nuzzo, M M; Calabria, M; Peltrini, R; Castiglioni, S; Bracale, U; Cervone, C; Rega, D; Caliendo, D; Benetti, E; Delrio, P; Guarino, R; de Franciscis, S; Coppolino, F; Romano, F M; Selvaggi, F; Pellino, G; Sciaudone, G; Selvaggi, L; de Stefano, M; Resendiz, A; Carosso, F; Degiuli, M; Salusso, P; Reddavid, R; Benetti, S; Callari, C; Di Miceli, D; Pardo, D; Sabatino, G; Licari, L; Lirosi, M C; Sorce, V; Peri, A; Mori, A; Pugliese, L; Filardo, M; Nuccio, P; Dominioni, T; Ciciliot, M; Giuseppina, F; Angelo, F; Raffaele, G; Michele, M; Roberto, P; Mondini, A; Muratore, A; Valentino, C; Calabro, M; Danna, R; Cremonini, C; Sbarbaro, C; Tartaglia, D; Coccolini, F; Chiarugi, M; Musetti, S; Pagani, S; Neri, C M; Leoni, C; Rossi, E; Randisi, E; Puccini, M; Buccianti, P; Balestri, R; Vasale, A O; Crescentini, G; Ranieri, G; Sinibaldi, G, I; Biondi, A; Sanesi, A P; Vacca, C; Lorenzon, L; Sollazzi, L; Persiani, R; Pezzuto, R; Ferroni, A F; Stipa, F; Volturo, L; Moretti, M; Tierno, S M; Marina, S; Mingoli, A; Fiori, E; Pugliese, F; Brachini, G; Carta, G; Sapienza, P; Lapolla, P; Mazzotta, E; Carannante, F; Capolupo, G T; Masciana, G; Sica, I; Caricato, M; Antonelli, S; Fiume, D; Spoletini, D; Lisi, G; Carlini, M; Menduni, V; Arturi, A; Proietto, B; de Lucia, C; Baldi, C; Passantino, D G; Romeo, G; Di Paola, M; Sensi, B; Sica, G; Siragusa, L; Dauri, M; Franceschill, M; Campanelli, M; Bellato, V; Porcu, A; Garau, A G Giuseppina; Masala, M L; Oggianu, S; Tedde, T; Perra, T; Pazzola, V; Venezia, D F; Roviello, F; Giacomini, G; Carbone, L; Marano, L; Verre, L; Marano, M; Ciccarese, A A; Bagnardi, F; Shahu, J; Siciliano, W; Iacomino, A; Armellin, C; Marson, F; Zanus, G; Santoro, G A; de Paoli, M; Grossi, U; Sekimoto, M; Kobayashi, T; Horiguchi, A; Koike, D; Yonekura, H; Kato, H; Yoshino, K; Arakawa, S; Asano, Y; Alawneh, F; Rajab, I; Ramadan, M; Al Masri, M; Al Qaisi, M; Alsamneh, M; Mubaidin, O; Al-Jarrah, A; Ababneh, H; Khdair, K; Tawarh, T; Sabri, W; Arida, Z A; Dzhumabekov, B; Klyshbayeva, D; Fakhradiyev, I; Ispbayeva, K; Nadyrov, M; Tanabayeva, S; Saliev, T; Jumanov, A; Aitbaeva, A; Arynov, A; Kulimbet, M; Maulenov, N; Dushimova, Z; Park, E Jung; Kim, H; Kang, J; Baik, S H; Song, Y; Kwak, H D; Kim, J; Son, J H; Chung, J S; Lee, H; Baek, J-H; Nam, K H; Lee, W-S; Jeon, Y; Kim, C W; Park, S-E; Lee, S-H; Son, G M; Ahn, H M; Lee, I Y; Kim, T K; Pcolkins, A; Sivins, A; Lobovs, D; Ancans, G; Kreice, I; Budnikova, I; Jelovskis, I; Emhareb, A; Abaidalla, A; Hammed, A; Khairallah, M; Jibreel, S S; Mohmmad, W A S; Hasan, W; Venskutonis, D; Daugela, E; Dainius, E; Juocas, J; Kutkevicius, J; Vaitkute, K; Bradulskis, S; Macas, A; Pauzas, H; Jokubauskas, M; Lizdenis, P; Budrikiene, R; Svagzdys, S; Saladzinskas, Z; Dulskas, A; Volkoviene, G; Makauskiene, J; Kuliavas, J; Bernotaite, V; Danys, D; Kontrimaviciute, E; Poskus, E; Kryzauskas, M; Jakubauskas, M; Poskus, T; Jotautas, V; Zakaria, A D; Kai, M W P; Zainy, R H M; Tan, S S; Zain, W Z W; Zakaria, Z; Yusoff, Z M; Raduan, F; Sagap, I; Razali, N Y Fazlina; Rahman, N Abdul; Kanthan, S B Chandra; Nie, Y Chih; Azman, Z A M; Ang, C W; Tang, C Y; Poh, K S; Ng, K; Hashim, N M; Xavier, R; Khong, T L; Amir, A S; Ali, C S Che; Yew, C K; Henry, F; Muniandy, J; Baharom, S; Eng, S C Ren; Hu, F Su-Min; Amin-Tai, H; Jabar, M F; Satar, M H S Abdul; Fathi, N Q; Rao, P S; Podesta, A M Camilleri; Cini, C; Psaila, J; Debono, M; Sammut, M; Spiteri, N; Andrejevic, P; Muro, A Galaviz; Leon, B Perez; Perez, J A Valenzuela; Quinonez, J R Acosta; Vera, M T Ramirez; Gutierrez, V M Maciel; Bobadilla, B Jimenez; Martinez, C M; Rendon, J L de Leon; Hererro, J A Villanueva; Cuichan, M V Y; Baez, N Fernandez; Prevost, P G; Hoyos-Torres, A; Ruiz-Munoz, E A; Alvarez-Bautista, F E; Ortiz-Mendez, G; Zamudio-Bautista, J L; Salgado-Nesme, N; Vergara-Fernandez, O; Sanchez-Valdivieso, E; Martinez, G; Navarrete-Aleman, J; Perez-Arellano, J; Maldonado-Barron, R; Hernandez-Krauss, R; Ousadden, A; Benjelloun, E B; Bzikha, I; Ibnmajdoub, K; Mazaz, K; Marghich, O; Touzani, S; Benkabbou, A; Souadka, A; Ahmadi, B E; Zaari, F; Laamri, I; Majbar, M A; Mohsine, R; Van, C Berlo; Seuren, D; Gillissen, F; Aarts, F; Konsten, J; Van, M Heinsbergen; Schlooz, S; Naiqiso, A; Merrie, A; Varghese, C; Pugh, F; Bissett, I; Wilson, K; Mitchell, S; Dawson, C; Hill, C; Wright, D; Hubley, S; Lin, A; Jones, D; Siggins, L; Fagan, P; Wu, S; Ekwesianya, A; Nwoye, C; Agara, D; Ejiofor, G; Sundaynweke, N; Kwentoh, N; Ewah, R; Aremu, A; Ballah, A; Ningi, A; Ohia, E; Mienda, I; Aliyu, M; Oloko, N; Okunlola, A; Abiyere, H; Bolanle, O E; Babatunde, O; Fatudimu, S; Orewole, T; Mba, E Louis; Felix, M S; Abdulfatah, M; Ibrahim, N; Masoro, U; Fakoya, A; Irabor, D; Anyadike, F; Ulasi, I; Orji, M; Afuwape, O; Ayandipo, O; Adeyeye, A; Aremu, I; Adegboye, K; Gbadegesin, P; Aminu, B; Aghadi, I K; Makama, J G; Joshua, S; Kache, S A; Sheshe, A A; Bala, A M; Garzali, I U; Abdullahi, M M M; Muhammad, N; Umar, N A; Muhammad, S; Okoye, A; Emegoakor, C; Nwosu, C; Egwuonwu, O A; Ekwunife, O; Amadigwe, R; Ojiakor, S; Akere, A; Okereke, C; Olaleye, O; Ige, O; Olubayo, O; Olatiilu, T; Idris, M; Shehu, A; Oluyori, D; Nwabuoku, E; Ukwubile, L; Bashir, M; Daniyan, M; Rauf, H; Ali, M; Zakaria, M; Hameed, M; Amanullah, N; Chawla, T; Waqar, U; Jamal, A; Butt, A; Kerawala, A; Samson, S; Dodhy, A A; Gill, A J; Malik, A; Ali, D; Mohsin, H; Afzal, M F; Batool, Sana; Suleman, A; Khalid, J; Zafar, M; Dilawar, M; Janjua, M H; Sarwar, M Z; Naqi, S A; Akbar, A; Afzal, A; Anwar, J; Gondal, K M; Shaukat, M; Waheed, M; Sohail, M; Mukhtiar, N; Ammar, A S; Hussain, A; Khan, A N; Sarwar, A; Khan, I; Khattak, S; Oqaili, B; Saada, B; Zatari, D; Jubran, F; Hamdan, F; Emar, M; Alawi, R; Jacome, G; Insturain, I; Arauz, J; Hurtado, M; Beron, R, I; Castano, R; Cao, V H Bruno; Kwiatkowski, A; Dobkowski, G; Bartosiak, K; Waledziak, M; Mozanski, M; Zadrozna, M; Kowalewski, P; Fiedziuk, A; Watroba, A; Los, A; Sitarska, M; Rzaca, M; Zawadzki, M; Czarnecki, R; Tavares, C; Santos, F; Borges, F; Real, J Corte; Lima, M J; Carlos, S; Pereira, V; Pacheco, A; Gomes, G; Pimenta, J; Elisiario, L; Jervis, M; Goncalves, V; Pedro, V; Jordao, D; Neves, F Reis; Conceicao, L; Angelo, M D; Marques, P; Saraiva, R Prata; Caroco, T Vieira; Windels, A; Machado, A; Ribeiro, C; Velez, C; Oliveira, J; Melo, M R; Lima, R; Pires, A; Lareiro, C; Martins, R; Revez, T; Martins, A; Cardoso, D; Alegre, I; Estevao, P; Andrade, D; Gomes, D C; Duarte, M J; Custodio, P; Nemesio, R A; Rodrigues, S; Correia, A; Domingos, H; Herrando, I; Azevedo, J; Fernandez, L; Azevedo, P; Vieira, P; Torre, A; Amado, A; Paiva, M; Saraiva, R; Costa, S; Mendes, T; Queiros, T; Silva, A; Faustino, A; Freitas, A; Mendes, J; Amaral, L; Quintanilha, R; Coelho, A M; Ribeiro, A; Pinto, C; Ribeiro, N; Reis, R; Fernandes, V; Sanches, A; Amorim, E; Miguel, I; Rachadell, J; Sanches, Madalena; Oliveira, S; Baptista, V; Roxo, A; Devesa, H; Teslyak, O; Barradas, R; Marques, S; Martins, S; Pepino, S; Deus, A C; Ferreira, A; Marinho, D; Sousa, D; Martins, M J; Matias, N; Pinto, A; Correia, D; Amado, F; Cordeiro, L; Morales, M; Lamas, M; Marcal, S; Rodrigues, A, I; Santos, A; Marcal, A; Oliveira, A; Gomes, C; Ferreira, C; Marques, R; Chitul, A; Alexandrescu, C; Bezede, C; Cristian, D; Mandi, D; Grama, F; Ungureanu, R; Stoica, B; Diaconescu, C; Ciubotaru, C; Tanase, I; Grintescu, I; Negoi, I; Negoita, V M; Calin, C; Simeanu, C; Ciotarla, D C; Caltea, M; Mirica, R M; Luca, A; Pasca, A; Vlad, C; Bonci, E-A; Stefanescu, I; Achimas-Cadariu, P A; Gata, V A; Capusan, A; Petrisor, C; Dindelegan, G; Seicean, R; Scurtu, R; Bintintan, V; Fagarasan, V; Ionescu, C; Crisan, D; Zanc, L; Ene-Cocis, M-, V; Muresan, M-S; Mihalcea, S M; Dudric, V; Musina, A-M; Ristescu, A-, I; Roata, C-E; Moglan, M; Dimofte, M-G; Lunca, S; Iacob, S; Dychko, A; Litvin, A; Kapustina, A; Provozina, A; Anokhin, E; Zabiyaka, M; Shin, A; Djumabayev, K; Kuznetsova, M; Gordeyev, S; Kochkina, S; Mamedli, Z; Markaryan, D; Galliamov, E; Semina, E; Agapov, M; Malahov, P; Garmanova, T; Kakotkin, V; Zaycev, A; Sumbaev, A; Bedzhanyan, A; Orman, E; Petrenko, K; Bredikhin, M; Frolova, Y; Tulina, I; Bashilkina, O; Tsarkov, P; Rodimov, S; Stamov, V; Balaban, V; Alexnder, A; Yanishev, A; Rogozhev, D; Yakunina, N; Chubukova, N; Nugmanov, R; Karachun, A; Petrov, A; Domanskiy, A; Panaiotti, L; Smolina, M; Sapronova, T; Pelipas, Y; Zagaynov, E; Khrykov, G; Davidovskaja, L; Burlov, N; Mankevich, N; Tverdohlebova, T; Bogatikov, A; Lodygin, A, V; Krasnoselsky, C; Vasiukova, E-S; Kopteyev, N R; Ovchinnikov, T; Kashchenko, V A; Novikova, A; Terentyeva, E; Kuleshov, O; Pavlov, R; Koshel, A; Kostromitsky, D; Drozdov, E; Klokov, S; Camacho, A; Khan, F N; Al Bandar, M; Shamim, R; Chowdhury, S; Kovacevic, B; Krdzic, I; Zdravkovic, M; Kenic, M; Milentijevic, M; Petkovic, N; Radulovic, R; Ngu, J; Teo, N Z; Singh, P A; Ong, S Y; Li, S; Siew, B En; Chee, C; Koh, J J M; Lee, K Y; Tan, K K; Wong, S C; Loh, W; Pujol, A F; Rubio, J C; Farres, L P; Vendrell, L L; Del Olmo, M I Urena; Pedregosa, A B; Galmes, C; Luckute, D; Casanova, D; Artigot, M; Guedes, X; Olivella, Y; Sarda, M S; Toscano, M J; Damieta, M P; Pera, M; Goncalvez, S A; Galvez, S T; Ruiz, S S; Espin-Basany, E; Marinello, F; Villarino-Villa, L; Heras, M Vega-Las; Martin-Sanchez, R; Mata, R Mata; Blanco-Colino, R; Otero, A; de Lacy, A Maria; Sanahuja, J M; Bravo, R; Ferraz, T; Gonzabay, V; Gonzalez, F; Menendez, P; Del Castillo, V C Garcia; Lopez-Pelaez, V M; Lillo-Garcia, C; Tauler, E M; Sanchez-Guillen, L; Manresa, M C Estan; Perez, S L; Llopis, S Q; Rubio, A, V; Castillo, E R; Miramon, F J Jimenez; Rodriguez, J L Ramos; Rizo-Lamberti, L A; Garrido, P G; Carneros, V J; Alfonso, B A; Sierra, B G; Amador, C G; Gomendio, M D Picardo; Palomino, M V Romo; Llamas, R de La Plaza; Cafranga, E G; Ramos, J L Esteban; Estudillo, M C; Perez, R E; Pernas, R M; Fernandez, S de Lebrusant; Bautista, W M Sanchez; Llamazares, A L; Valbuena, A L; Moran, L A; Alvarez, L J; Raposo, L G; Ceron, S F; Gonzalez, T E; Calvo, A C; Valcarcel, C R; Pena, J Perez; Gomez, L M Jimenez; Diez, M C; Lindenbaum, P D; Mata, S K; Ruiz-De-La-Hermosa, A; Abad-Motos, A; Toribio-Combarro, B; Ripolles-Melchor, J; Fuenmayor-Valera, M L; Ortega-Domene, P; Loscos, A; Del Pueblo, C S; Dziakova, J; Muguerza, J M; Carlin, P S; Anula, R; Mouvet, Y; Forero-Torres, A; San Andres, B D; Marcos, C M; Rubio, I; Pascual, I; Yague, J; Alcolea, N G; Alonso, A; Dieguez, B; Ibanez, I; Perez, J L; Losada, M; Garcia-Conde, M; Hernandez, M; Blazquez-Martin, A; Vera-Mansilla, C; Mendoza-Moreno, F; Hernandez-Salvan, J; Diez-Alonso, M; Hernandez-Juara, P; Barrena-Blazquez, S; Minaya-Bravo, A M; Galvan-Perez, A; Miguel-Mendez, C S; Gonzalez-Gonzalez, E; Alvarez-Diez, M; Garcia-Urena, M A; Llorente-Moreno, M; Ruiz-Lozano, C; Colas-Ruiz, E; Perez-Calvo, J; Gomila-Sanso, J A; Alvarez-Llano, L; Serrano-Fuentes, S C; Soto-Montesinos, C; Dedeu-Bastardas, I; Perez-Reche, I; Labro-Ciurans, M; Pardo-Lopez, S; Perez, E G; Fernandez, I O; Canals, L O; Espino, P C; Ruano, P G; Ricardo, V; Ros, E P; Manuel, E M; Buleje, J A Benavides; Prats, M M Carrasco; Banos, P A Parra; Gonzalez, P M; Celdran, R G; Pellicer-Franco, E M; Valero-Navarro, G; Vicente-Villena, J P; Martinez-Mercader, M M; Baeza-Murcia, M; Mengual-Ballester, M; Soria-Aledo, V; Fernandez-Martinez, D; Varela-Rodriguez, L; Garcia-Florez, L J; Fernandez-Hevia, M; Gonzalez-Diaz, M J; Fernandez-Arias, S; Puertas, C P; Carvajal, E de San Pio; Cebolla, E S; Brainsa, E; Bayo, J M Muros; Castro, M C; Blanco, R R; Gutierrez, E; Pinto, F L; Alegre, J M; Flores, N; O'Sullivan, S N; Fernandez, B F; Alonso, J E; Conde, J G Ais; Ropero, N M; Bayon, R A; Dominguez, S H; Ramirez, S; de Pablos, A M; Perez-Sanchez, A; Cano-Matias, A; Del-Rio-Lafuente, F-J; Caballero-Delgado, J; Valdes-Hernandez, J; Gomez-Rosado, J-C; Martinez, C; Cholewa, H; Sancho-Muriel, J; Alberola, M J; Navasquillo, M; Primo, V; Moreno, V; Espi-Macias, A; Moro-Valdezate, D; Carrascosa-Morales, I; Martin-Arevalo, J; Soro-Domingo, M; Garcia-Botello, S; Pla-Marti, V; Abellan, A M; Perez, C M; Cortes, G F Valderas; Blasco, L F; Chornet, M R; Martin, R S; Romero-De Diego, A; Vazquez-Fernandez, A; Pascual, A; De Andres-Asenjo, B; de Heredia, J B; Ruiz-Soriano, M; Rodriguez-Jimenez, R; Iribarren, E M; Rodriguez, E V Flores; Garcia, M D C Casas; Garcia-Senorans, M P; Rodriguez, P F; Santos, R S; Curras, R P; Vigorita, V; Roche, C G; Delgado, E; Lafuente, F; Gascon, I; Mallen, M V Duque; Saudi, S; Fraj, V; Gomez, M E; Santos, E G; Mena, E A; Mantecon, J, V; Garcia, S S; Fernandez-Camunas, A; Wickramasinghe, D; de Zoysa, I; Samarasekera, N; Wickramarathne, R; Dassanayake, V; Balathayalan, Y; de Silva, D; Perera, M; Pulleperuma, S; Jayasekara, S; Wijenayake, W; Gunetilleke, B; Abeysinghe, N; Chandrasinghe, P; Kumarage, S; Abdalradiy, A G; Widatalla, A B H; Ahmed, A Y; Mohamed, H A; Hamid, H K S; Ali, M H; Eldin, S J; Agger, E; Jutesten, H; Lindgren, J; Lepsenyi, M; Azhar, N; Buchwald, P; Hansdotter, P; Ekepil, A; Brandstrom, G; Smedberg, J; Schiffer, E; Ris, F; Longchamp, G; Meyer, J; Dupret, L; Buchs, N; Galetti, K; Regusci, L; Grischott, M; Malugani, M; Mouhandes, A El-Fattah; Danial, A K; Khayat, M; Sbahi, M H Eddin; Marawy, M K; Abdullah, M A; Douba, Z; Mansour, A; Niazi, A; Hamza, A; Mohamad, A H; Awead, M; Mohammad, S; Salloum, S; Al Jabar, A; Zazo, A; Shebli, B; Ayoub, K; Younes, L; Bannoud, M H; Zazo, R; Saad, A; Hamdan, A; Wakkaf, H; Adra, L; Souliman, M; Anton, M; Hannouf, S; Wang, J Y; Li, K L; Cheng, K, I; Ji, S J; Hsieh, Y C; Parlak, E A; Demir, M; Kara, U; Peker, Y S; Yigit, D; Unal, N; Iflazoglu, N; Yalkin, O; Topal, S; Gulcu, B; Ozturk, E; Gumbelek, G; Terkanloglu, S; Koklucan, A; Ince, G; Sen, M; Isik, O; Kural, S; Akesen, S; Yilmazlar, T; Sungurtekin, H; Sungurtekin, U; Vural, U; Ozgen, U; Isik, A; Onk, D; Kurnaz, E; Ozker, T S; Ipek, A; Ferlengez, A; Erturk, C; Tatar, C; Sevik, H; Akay, O; Sensoy, O; Hayirlioglu, M B; Aktas, S; Ozben, V; Aliyeva, Z; Mutlu, A U; Gokay, B, V; Saracoglu, C; Aytac, E; Gulmez, M; Isik, M U; Hacim, A; Akbas, A; Soyhan, F; Turgut, M A; Demirgan, S; Meric, S; Altinel, Y; Baris, B; Akova, E; Kahraman, E; Kucuk, H F; Saracoglu, K T; Kaya, S; Lel, S; Gurbulak, E K; Caz, E; Kostek, M; Mihmanli, M; Yazici, P; Oba, S; Kirkan, E F; Ulgur, H S; Kalin, M; Dinkci, M D; Ozkan, O F; Duzgun, O; Ozturk, S; Zengin, A K; Askar, A; Sanli, A N; Erginoz, E; Ozcelik, M F; Ergun, S; Uludag, S S; Kara, D; Yilmaz, G; Sarici, I S; Kara, Y; Incesu, A; Arican, C; Atici, S D; Kaya, T; Gezer, T; Kirmizi, Y; Kamer, E; Aydin, G; Namdaroglu, O; Adakaya, S; Canda, A E; Ozzeybek, D; Coskun, N; Sokmen, S; Ozkardesler, S; Bisgin, T; Miftari, A; Caliskan, C; Akgun, E; Avseren, G; Deniz, N; Bozbiyik, O; Yoldas, T; Guresin, A; Zayakov, G; Posteki, G; Utkan, N Z; Tatar, O C; Guler, S A; Mantoglu, B; Demirel, E; Akin, E; Gonullu, E; Altintoprak, F; Palabiyik, O; Bayhan, Z; Ciftci, A B; Colak, E; Aybar, E; Celik, H K; Eraslan, H; Yemez, K; Ozbilgin, S S; Senol, S; Gultekin, F A; Piskin, O; Guler, O; Karadere, Y; Kakeeto, A; Oguttu, B; Sikakulya, F K; Lule, H; Rybachuk, A; Shudrak, A; Beznosenko, A; Lisnyy, I; Rozhkova, V; Zvirych, V; Alawlaqi, D; Jamali, F E; Al Balooshi, I; Albers, M; Al Ali, N; Church, R; Dudas, G; Wells, J; Pavlova, M; Sebastiani, S; Paterson, C; Kaushal, M; Patel, P; Panchal, S; Handa, S; Tezas, S; Zaidi, S-N; Raj, G; Wright, J; Hallam, S; Karandikar, S; Gates, Z; Marshall, A; Thompson, A; Tennakoon, A; Rao, M; Callan, R; Tufail, S; Rajendran, G; Polisetty, K; Husain, N; Clarke, N; Naranayanasamy, S; Hallett, A; Lorejo, E; Ward, N; Antakia, R; Xanthis, A; Simillis, C; Tweedle, E; Panagiotopoulou, I; Grimes, L; Mounstephen, L; Bocancia, R; Carden, C; Lynch, J; Noveros, M S; Shaalan, R; Khalil, T; Marshall, W; Hodge, K; Balfour, J; Mcintosh, K; Buijs, L; Potter, M A; Yule, M; Vaughan-Shaw, P G; Smith, S; Anderson, T; Mcdermott, F D; Daniels, I R; Tapp, J; Smart, N; Rajaretnam, N; Bethune, R; Clark, T; Delimpalta, C; Liao, C; Banham, G; Induruwage, L; Velchuru, V; Lawrence, A; Rahman, A; Bennett, J; Badawi, M; Harshen, R; Bhargava, A; Gorrela, K; Jumah, M; Venn, M; Hanson, M; Arya, S; Atendido, T; Shrestha, A; Cook, E; Rakhimov, I; Collins, J; Alamin, N; Vigneswaran, N; Basnyat, P; Shamardal, A; Chacko, A; Wanshantha, D; Bisheet, G; Ebdewi, H; Abdellatif, M; Adu-Poku, P; Tore, A; Adams, F; Allen, K; Ahmed, K; Kulkarni, N; Chitnis, A; Patel, H; Magsino, J; Sarodaya, V; Minicozzi, A; Dempsy, C; Ahmed, H; Jayasinghe, J D; Okail, M H; Thaha, M; Hallworth, S; Parmar, C; Chua, L; Pizanias, M; Samin, R; Young, T; Sagar, J; Yorkmui, L; Cirocchi, N; Ahmed, S; Barreda, S C; Kudchadkar, S; Baker, A; Jayasankar, B; Balasubramaniam, D; Jackson, J; Abdelsaid, K; Hassan, M; Shetty, S; Coldwell, C; Davies, E; Nader, H; Raistrick, M; Ryska, O; Hawkin, P; Raymond, T; Witjes, C; Van de Steen, K; Crabtree, N; Boyce, S; Somera, W; Woodward, A; Ryan, K; Kassai, M; Aleem, M; Keogh-Bootland, S; Ghosh, A; Rixson, D; Lewis, E; Lynch, N; Shovelton, C; Zywicka, E; Guest, F; Barton, J; Purnell, R; Bamford, R; Teare, T; Adams, B; Chmielewski, G; Smith, I; Smith, L; Connolly, L; Niblett, R; Singh, A; Halliwell, G; Paraoan, M; Doree, N; Asaad, P; Kilbride, C; Carpenter, H; Wilson, J; Fletcher, J; Vijayagopal, K A; Abbakar, M; Zaimis, T; Walsh, A; Kubisz-Pudelko, A A; Nono, J; Pippard, L; Chowdhary, M; Dalton, R; Moussa, T; Dominguez, F; Solla, G; Curbelo, J; Laurini, M; Viola, M; Brito, N; Al-Alnsi, A; Al-Naggar, H; Saryah, L; Al-Shehari, M; Alsayadi, R; Al-Hutheifi, R; Shream, S

Afiliaciones

Resumen

Background: Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks. Methods: The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned. Results: A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31). Conclusion: Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov).

Palabras clave