Thyrotoxicosis and hyperthyroidism
Publicado en:Medicine: Programa de Formación Médica Continuada Acreditado. 14 (14): 777-790 - 2024-06-01 14(14), DOI: 10.1016/j.med.2024.07.002
Autores: López-Ruano M; Sager C; Justel-Enríquez A; Jiménez-Blanco S
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Resumen
Thyrotoxicosis is a clinical condition secondary to excess thyroid hormones (TH). It can be caused by increased synthesis and release of TH by the thyroid gland (hyperthyroidism, the most common cause) as well as by thyroid inflammation and destruction, ectopic production, or exogenous administration of TH. The diagnosis is biochemical and based on the determination of thyroid stimulating hormone (TSH) and thyroid hormones (thyroxine and triiodothyronine). To plan effective treatment, it is crucial to identify the underlying cause. Graves-Basedow disease is the most common cause, followed by toxic multinodular goiter and toxic thyroid adenoma. Less frequent, although relevant, are thyroiditis, extrathyroidal TH production, and factitious thyrotoxicosis. Some imaging tests, such as a Doppler ultrasound and thyroid scintigraphy, are helpful in the etiological diagnosis. The goal of treatment is to achieve symptoms control and reduce TH synthesis and secretion through the use of drugs or radical treatments (radioiodine or surgery).
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Análisis de liderazgo de los autores institucionales
Existe un liderazgo significativo ya que algunos de los autores pertenecientes a la institución aparecen como primer o último firmante, se puede apreciar en el detalle: Primer Autor (López-Ruano M.) y Último Autor (Jiménez-Blanco S.).