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Martín-González N.Autor o CoautorPérez-Illana M.Autor o CoautorHernando-Pérez M.Autor o Coautor

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Adenoviruses (Adenoviridae) and Their Structural Relatives

Publicado en:Encyclopedia of Virology: Volume 1-5, Fourth Edition. 1-5 329-344 - 2020-01-01 1-5(), DOI: 10.1016/B978-0-12-814515-9.00035-7

Autores: Condezo GN; Martín-González N; Pérez-Illana M; Hernando-Pérez M; Gallardo J; San Martín C

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Adenoviruses have complex, non-enveloped icosahedral capsids with triangulation number pseudoT = 25. Trimers of the major coat protein (hexon) form the icosahedral facets, while the vertices are occupied by a pentamer of penton to which trimeric fibersare attached. Four types of minor coat proteins complete the shell, modulating the quasi-equivalent icosahedral interactions. The dsDNA genome, bound to a large amount of positively charged proteins, forms the non-icosahedral core. Hexon monomers fold as a double β-barrel perpendicular to the capsid surface. Viruses infecting very different organisms, from bacteria to archaea to humans, also use this fold to build their infectious particles.

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