{rfName}
Mo

Indexed in

License and use

Citations

4

Altmetrics

Analysis of institutional authors

Martín-Hernández DAuthorUlecia-Morón CAuthorPereira M.p.Author or co-author of chapter in book
Share
Publications
>
Chapter

Monoaminergic system and antidepressants

Publicated to:The Neuroscience of Depression: Features, Diagnosis, and Treatment. 1-2 345-355 - 2021-01-01 1-2(), DOI: https://doi.org/10.1016/B978-0-12-817933-8.00093-1

Authors: Martín-Hernández D; Ulecia-Morón C; Bris ÁG; Caso JR; Pereira MP

Affiliations

Instituto de Salud Carlos III - Author
Universidad Autónoma de Madrid - Author

Abstract

Abstract The standard pharmacological treatment of the major depressive disorder (MDD) is still grounded in a monoaminergic hypothesis of depression. As a consequence, many current antidepressant treatments pursue to heighten monoamine neurotransmissions. Thus, monoamine reuptake inhibitors, as well as monoamine receptor modulators, have been developed as antidepressants and nowadays, they are used widely in clinical practice and they still epitomize the first pharmacological approach to treat mood disorders. In this chapter, the main antidepressants involved in the enhancement of the monoaminergic neurotransmission are being reviewed. Particularly, the chapter focuses on the serotonergic, noradrenergic, and dopaminergic neurotransmissions and on the antidepressant drugs acting on these neurotransmissions. Finally, a short review of the therapeutic implications of less frequent monoamines (i.e., histamine, melatonin, and tryptamine hallucinogens) is also performed at the end of the chapter.

Keywords
AntidepressantsDopamineHistamineMajor depressive disorderMelatoninMonoaminergic systemMonoaminesNoradrenaline/norepinephrineSerotoninTryptamine hallucinogens

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2025-05-03:

  • Scopus: 4
Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-05-03:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 15 (PlumX).
Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (MARTIN COFRECES, NOA BEATRIZ) .