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Grant support

M.L.L.-M. was supported by the European Research Council (ERC) (ERC-CoG-2020-101001916), Spain's Ministry of Economy and Competitiveness (PID2020-113007RB-I00, SAF-2017-82185-R, and RYC-2015-171899), the Alzheimer's Association (2015-NIRG-340709, AARG-17-528125, and AARG-17-528125RAPID), the Association for Frontotemporal Degeneration (2016 Basic Science Pilot Grant Award), and the Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED, Spain). Institutional grants from the Fundacion Ramon Areces and Banco de Santander to CBMSO. are also acknowledged. The salary of J.T.-R. was supported by a doctoral fellowship from the Universidad Autonoma de Madrid (FPI-UAM 2017 program). The salary of E.P.M.-J. was supported by a 2018 Neuroscience doctoral fellowship from the Fundacion Tatiana Perez de Guzman. The salary of M.F.-G. was supported by a Formacion de Personal Investigador (FPI) contract, associated with the SAF-2017-82185-R grant (M.L.L.-M.) and supported by the Spain's Ministry for Economy and Competitiveness (PRE2018-085233). The salary of C.B.R.-M. is supported by "Subvenciones para la promocion de empleo joven e Implantacion de la garantia juvenil en I+D+i 2018"(PEJ2018-001725-A), awarded by Spain's Ministry of Economy and Competitiveness to M.L.L.-M.

Analysis of institutional authors

Terreros-Roncal JAuthorLlorens-Martín MCorresponding Author

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November 3, 2021
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Article
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Impact of neurodegenerative diseases on human adult hippocampal neurogenesis

Publicated to:SCIENCE. 374 (6571): eabl5163-eabl5163 - 2021-11-26 374(6571), DOI: 10.1126/science.abl5163

Authors: Terreros-Roncal J, Moreno-Jiménez EP, Flor-García M, Rodríguez-Moreno CB, Trinchero MF, Cafini F, Rábano A, Llorens-Martín M

Affiliations

CIEN Fdn, Neuropathol Dept, Madrid, Spain - Author
Ctr Networked Biomed Res Neurodegenerat Dis CIBER, Madrid, Spain - Author
Leloir Inst IIBBA CONICET, Lab Neuronal Plastic, Buenos Aires, DF, Argentina - Author
Univ Autonoma Madrid UAM, Ctr Biol Mol Severo Ochoa CBMSO, Spanish Res Council CSIC, Dept Mol Neuropathol, Madrid, Spain - Author
Univ Autonoma Madrid, Fac Sci, Dept Mol Biol, Madrid, Spain - Author
Univ Europea Madrid, Fac Biomed & Hlth Sci, Madrid, Spain - Author
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Abstract

[Figure: see text].

Keywords

neuronsnichesufficientCell-proliferation

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal SCIENCE due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2021, it was in position 2/74, thus managing to position itself as a Q1 (Primer Cuartil), in the category Multidisciplinary Sciences. Notably, the journal is positioned above the 90th percentile.

This publication has been distinguished as a “Highly Cited Paper” by the agencies WoS (ESI, Clarivate) and ESI (Clarivate), meaning that it ranks within the top 1% of the most cited articles in its thematic field during the year of its publication. In terms of the observed impact of the contribution, this work is considered one of the most influential worldwide, as it is recognized as highly cited. (source consulted: ESI Nov 14, 2024)

And this is evidenced by the extremely high normalized impacts through some of the main indicators of this type, which, although dynamic over time and dependent on the set of average global citations at the time of calculation, already indicate that they are well above the average in different agencies:

  • Normalization of citations relative to the expected citation rate (ESI) by the Clarivate agency: 10.63 (source consulted: ESI Nov 14, 2024)
  • Weighted Average of Normalized Impact by the Scopus agency: 42.2 (source consulted: FECYT Feb 2024)
  • Field Citation Ratio (FCR) from Dimensions: 45.4 (source consulted: Dimensions Jul 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-07-05, the following number of citations:

  • WoS: 147
  • Scopus: 173
  • Europe PMC: 80

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-07-05:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 274.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 274 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 471.3.
  • The number of mentions on the social network Facebook: 3 (Altmetric).
  • The number of mentions on the social network X (formerly Twitter): 235 (Altmetric).
  • The number of mentions in news outlets: 39 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.

Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Argentina.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (TERREROS RONCAL, JULIA) and Last Author (LLORENS MARTIN, MARIA VICTORIA).

the author responsible for correspondence tasks has been LLORENS MARTIN, MARIA VICTORIA.