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Analysis of institutional authors
Barbáchano AAuthorFernández‐barral AAuthorPrieto IAuthorRodríguez‐salas NAuthorOrganoids and colorectal cancer
Publicated to:Cancers. 13 (11): 2657- - 2021-06-01 13(11), DOI: 10.3390/cancers13112657
Authors: Barbachano, Antonio; Fernandez-Barral, Asuncion; Bustamante-Madrid, Pilar; Prieto, Isabel; Rodriguez-Salas, Nuria; Larriba, Maria Jesus; Munoz, Alberto
Affiliations
Abstract
Organoids were first established as a three‐dimensional cell culture system from mouse small intestine. Subsequent development has made organoids a key system to study many human physiological and pathological processes that affect a variety of tissues and organs. In particular, organoids are becoming very useful tools to dissect colorectal cancer (CRC) by allowing the circumvention of classical problems and limitations, such as the impossibility of long‐term culture of normal intestinal epithelial cells and the lack of good animal models for CRC. In this review, we describe the features and current knowledge of intestinal organoids and how they are largely contributing to our better understanding of intestinal cell biology and CRC genetics. Moreover, recent data show that organoids are appropriate systems for antitumoral drug testing and for the personalized treatment of CRC patients.
Keywords
Quality index
Bibliometric impact. Analysis of the contribution and dissemination channel
The work has been published in the journal Cancers due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2021, it was in position 60/245, thus managing to position itself as a Q1 (Primer Cuartil), in the category Oncology.
From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 3.09. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)
This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:
- Weighted Average of Normalized Impact by the Scopus agency: 3.36 (source consulted: FECYT Feb 2024)
- Field Citation Ratio (FCR) from Dimensions: 11.73 (source consulted: Dimensions May 2025)
Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-05-18, the following number of citations:
- WoS: 34
- Scopus: 40
- Europe PMC: 27
- OpenCitations: 39
Impact and social visibility
Leadership analysis of institutional authors
There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (BARBACHANO BECERRIL, ANTONIO) and Last Author (Munoz A).