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Impact on the Sustainable Development Goals (SDGs)

Analysis of institutional authors

Gomez-Lopez GCorresponding Author

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April 16, 2021
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Article

DREIMT: a drug repositioning database and prioritization tool for immunomodulation

Publicated to: BIOINFORMATICS. 37 (4): 578-579 - 2021-02-15 37(4), DOI: 10.1093/bioinformatics/btaa727

Authors:

Troulé K, López-Fernández H, García-Martín S, Reboiro-Jato M, Carretero-Puche C, Martorell-Marugán J, Martín-Serrano G, Carmona-Sáez P, Glez-Peña D, Al-Shahrour F, Gómez-López G
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Affiliations

Bioinformatics Unit, SpCanish National Cancer Research Centre (CNIO), Madrid, Spain. - Author
Biomed Res Ctr CINBIO, Sing Res Grp, E-36310 Vigo, Spain - Author
Centre for Genomics and Oncological Research (GENYO), Granada, Spain. - Author
Department of Computer Science, University of Vigo, Ourense, Spain. - Author
SING Research Group, CINBIO - Biomedical Research Centre (University of Vigo), IIS Galicia Sur - Galicia Sur Health Research Institute (SERGAS-UVIGO). - Author
Spanish Natl Canc Res Ctr CNIO, Struct Biol Dept, Bioinformat Unit, Madrid 28029, Spain - Author
Univ Granada, Ctr Genom & Oncol Res, Bioinformat Unit, PTS Granada,Pfizer,Andalusian Reg Govt, E-18016 Granada, Spain - Author
Univ Vigo, Dept Comp Sci, ESEI Escuela Super Ingn Informat, E-32004 Orense, Spain - Author
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Abstract

Drug immunomodulation modifies the response of the immune system and can be therapeutically exploited in pathologies such as cancer and autoimmune diseases.DREIMT is a new hypothesis-generation web tool which performs drug prioritization analysis for immunomodulation. DREIMT provides significant immunomodulatory drugs targeting up to 70 immune cells subtypes through a curated database that integrates 4,960 drug profiles and ∼2,6K immune gene expression signatures. The tool also suggests potential immunomodulatory drugs targeting user-supplied gene expression signatures. Final output includes drug-signature association scores, FDRs and downloadable plots and results tables.http://www.dreimt.org.Supplementary data are available at Bioinformatics online.© The Author(s) (2020). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
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Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal BIOINFORMATICS due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2021, it was in position 5/57, thus managing to position itself as a Q1 (Primer Cuartil), in the category Mathematical & Computational Biology. Notably, the journal is positioned above the 90th percentile.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-05:

  • Open Alex: 14
  • Google Scholar: 11
  • WoS: 6
  • Europe PMC: 7
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-05:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 28.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 28 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 10.
  • The number of mentions on the social network X (formerly Twitter): 17 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
Continuing with the social impact of the work, it is important to emphasize that, due to its content, it can be assigned to the area of interest of ODS 3 - Ensure healthy lives and promote well-being for all at all ages, with a probability of 77% according to the mBERT algorithm developed by Aurora University.
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: Last Author (GOMEZ LOPEZ, GONZALO).

the author responsible for correspondence tasks has been GOMEZ LOPEZ, GONZALO.

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