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Analysis of institutional authors

Ortgies, Dirk HorstAuthorCantarano AAuthorLifante JAuthorJaque DAuthor
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Autofluorescence-Free in Vivo Imaging Using Polymer-Stabilized Nd3+-Doped YAG Nanocrystals

Publicated to:ACS Applied Materials & Interfaces. 12 (46): 51273-51284 - 2020-11-18 12(46), DOI: 10.1021/acsami.0c15514

Authors: Cantarano, Alexandra; Yao, Jingke; Matulionyte, Marija; Lifante, Jose; Benayas, Antonio; Ortgies, Dirk H; Vetrone, Fiorenzo; Ibanez, Alain; Gerardin, Corine; Jaque, Daniel; Dantelle, Geraldine

Affiliations

Inst Ramon y Cajal Invest Sanitaria IRYCIS, Nanobiol Grp, Madrid 28034, Spain - Author
Institut Charles Gerhardt Montpellier - Author
Institut National de la Recherche Scientifique - Author
Instituto Ramón y Cajal de Investigación Sanitaria - Author
Univ Autonoma Madrid, Dept Fis Mat, Fluorescence Imaging Grp, Madrid 28049, Spain - Author
Univ Autonoma Madrid, Fac Med, Dept Fisiol, Fluorescence Imaging Grp, Madrid 28029, Spain - Author
Univ Grenoble Alpes, Inst NEEL, Grenoble INP, CNRS, F-38000 Grenoble, France - Author
Univ Montpellier, CNRS UMR 5253, ENSCM, ICGM, F-34296 Montpellier, France - Author
Univ Quebec, Ctr Energie Mat & Telecommun, Inst Natl Rech Sci, Varennes, PQ, Canada - Author
Universidad Autónoma de Madrid - Author
Universite Grenoble Alpes - Author
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Abstract

© 2020 American Chemical Society. Neodymium-doped yttrium aluminum garnet (YAG:Nd3+) has been widely developed during roughly the past 60 years and has been an outstanding fluorescent material. It has been considered as the gold standard among multipurpose solid-state lasers. Yet, the successful downsizing of this system into the nanoregimen has been elusive, so far. Indeed, the synthesis of a garnet structure at the nanoscale, with enough crystalline quality for optical applications, was found to be quite challenging. Here, we present an improved solvothermal synthesis method producing YAG:Nd3+ nanocrystals of remarkably good structural quality. Adequate surface functionalization using asymmetric double-hydrophilic block copolymers, constituted of a metal-binding block and a neutral water-soluble block, provides stabilized YAG:Nd3+ nanocrystals with long-term colloidal stability in aqueous suspensions. These newly stabilized nanoprobes offer spectroscopic quality (long lifetimes, narrow emission lines, and large Stokes shifts) close to that of bulk YAG:Nd3+. The narrow emission lines of YAG:Nd3+ nanocrystals are exploited by differential infrared fluorescence imaging, thus achieving an autofluorescence-free in vivo readout. In addition, nanothermometry measurements, based on the ratiometric fluorescence of the stabilized YAG:Nd3+ nanocrystals, are demonstrated. The progress here reported paves the way for the implementation of this new stabilized YAG:Nd3+ system in the preclinical arena.

Keywords
autofluorescence removalbioimagingblock copolymernanothermometryyag:nd3+ nanoparticlesAutofluorescence removalBioimagingBlock copolymerNanothermometryNear-infrared fluorescenceYag:nd nanoparticles 3+

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal ACS Applied Materials & Interfaces due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2020, it was in position 44/335, thus managing to position itself as a Q1 (Primer Cuartil), in the category Materials Science, Multidisciplinary.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations from Scopus Elsevier, it yields a value for the Field-Weighted Citation Impact from the Scopus agency: 1.79, which indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Field Citation Ratio (FCR) from Dimensions: 2.86 (source consulted: Dimensions May 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-05-15, the following number of citations:

  • WoS: 18
  • Scopus: 20
  • OpenCitations: 20
Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-05-15:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 33 (PlumX).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Canada; France.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Benayas Hernandez, Antonio) .