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Egido De Los Rios, JesusAuthorGonzalez Parra, Emilio JoseAuthorOrtiz Arduan, AlbertoAuthorBarril Cuadrado, GuillerminaAuthorGracia-Iguacel CCorresponding AuthorEgido JAuthor

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Review

Defining protein-energy wasting syndrome in chronic kidney disease: Prevalence and clinical implications

Publicated to:NEFROLOGIA. 34 (4): 507-519 - 2014-01-01 34(4), DOI: 10.3265/Nefrologia.pre2014.Apr.12522

Authors: Gracia-Iguacel C; González-Parra E; Barril-Cuadrado G; Sánchez R; Egido J; Ortiz-Arduán A; Carrero J

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Abstract

The presence of malnutrition in chronic kidney disease (CKD) is well-known. The discovery in the last 15 years of pathophysiological mechanisms that lead to this process, such as anorexia, the increase of protein catabolism and inflammation, has created the need for a new name by the International Society of Renal Nutrition and Metabolism (ISRNM): protein-energy wasting syndrome (PEW). This document's objectives are to propose the use of the term desgaste proteico energético (DPE) as a more accurate translation of the English term and to update the pathogenic mechanisms involved that are inherent to DPE (PEW). We simultaneously review the latest epidemiological evidence that highlight the relevance of malnutrition and its impact both on mortality and morbidity in CKD. Finally, we point out the need to redefine DPE (PEW) diagnostic criteria so that they are applicable to the Spanish population with CKD. We do not think that the criteria established by the ISRNM can be extrapolated to different populations, as is the case, for example, with interracial anthropometric differences. © 2014 Revista Nefrología.

Keywords

Chronic kidney diseaseProtein-energy wasting syndrome

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal NEFROLOGIA, and although the journal is classified in the quartile Q3 (Agencia WoS (JCR)), its regional focus and specialization in Urology & Nephrology, give it significant recognition in a specific niche of scientific knowledge at an international level.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 1.4. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 3.24 (source consulted: FECYT Feb 2024)
  • Field Citation Ratio (FCR) from Dimensions: 8.54 (source consulted: Dimensions Jun 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-06-07, the following number of citations:

  • WoS: 34
  • Scopus: 46
  • Europe PMC: 6
  • OpenCitations: 22

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-06-07:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 284.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 382 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 0.5.
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Sweden; Switzerland.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (GRACIA IGUACEL, CAROLINA MARTA) .

the author responsible for correspondence tasks has been GRACIA IGUACEL, CAROLINA MARTA.