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Sevilla Escribano, M TeresaAuthorMendiola Martin, Maria AntoniaAuthor

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October 19, 2020
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Thiohydrazone copper(II) complexes. The relationship between redox properties and superoxide dismutase mimetic activity

Publicated to: BIOELECTROCHEMISTRY AND BIOENERGETICS. 48 (1): 109-116 - 1999-02-01 48(1), DOI: 10.1016/S0302-4598(98)00231-1

Authors:

Ďuračková Z; Mendiola M; Sevilla M; Valent A
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Affiliations

Biochem. Clin. Biochem. - Author
Comenius University - Author
Universidad Autónoma de Madrid - Author
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Abstract

The redox behaviour of copper(II) complexes with the open chain ligand, benzilbisthiosemicarbazone, and the macrocyclic one [3,4,10,11-tetraphenyl-1,2,5,8,9,12,13-octaazacyclotetradeca-7,14-dithione-2,4,9,11-tetraene] has been explored by cyclic voltammetry. The half-wave potential values for the copper(II)/copper(I) redox couple and the spectral data obtained on dimethylsulfoxide (DMSO) solution agree with the superoxide dismutase (SOD)-mimetic activity of the complexes. The macrocyclic complexes show more positive reduction potential and more activity than the open chain derivatives. From our results it follows that the structure and conformation of ligand has influence on the redox potential of central atom in coordination compound. The changes in the coordination sphere are connected with the change of biological function of compounds represented by SOD-mimic activity. In addition, the L1H6 derivatives show quasireversible waves associated to Cu(II)/Cu(III) process. Copyright (C) 1999 Elsevier Science S.A.
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Keywords

Copper complexesHydrazone macroligandsRedox potentialSuperoxide dismutase

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal BIOELECTROCHEMISTRY AND BIOENERGETICS, and although the journal is classified in the quartile Q3 (Agencia WoS (JCR)), its regional focus and specialization in Biology, Miscellaneous, give it significant recognition in a specific niche of scientific knowledge at an international level.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-01-21:

  • WoS: 32
  • Scopus: 35
  • Europe PMC: 9
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-01-21:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 16.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 16 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 6.
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Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Slovakia.

the author responsible for correspondence tasks has been Mendiola M.

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