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Bernis, CAuthor
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Renal failure in temporal arteritis

Publicated to:American Journal Of Nephrology. 12 (5): 380-383 - 1992-01-01 12(5), doi: 10.1159/000168477

Bernis, C;

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Abstract

Summary: We report a case of biopsy-proven temporal arteritis and polymyalgia rheumatica with improved clinical symptoms with steroid treatment but with subsequent renal failure while on steroids. Kidney biopsy showed focal segmental necrotizing glomerulonephritis with crescents and small-vessel vasculitis. Treatment with methylprednisolone and cyclophosphamide achieved normalization of renal function. We emphasize the importance of kidney biopsy because of its therapeutic implications. The previous literature concerning renal disease in temporal arteritis is discussed.

Keywords: Aged; Biopsy; Complications; Cyclophosphamide; Drug therapy, combination; Female; Humans; Methylprednisolone; Prednisone

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