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Analysis of institutional authors

Sánchez-González M.c.Author

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December 14, 2025
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Diversity and composition of ocular microbiota in contact lens wearers: Efficacy of liposomal ozonated oil

Publicated to: Contact Lens & Anterior Eye. 48 (3): - 2025-06-01 48(3), DOI: 10.1016/j.clae.2025.102368

Authors:

Sánchez-González MC; Gallardo-Real I; Gutiérrez-Sánchez E; De-Hita-Cantalejo C; Capote-Puente R; Sánchez-González JM
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Affiliations

Universidad de Sevilla - Author

Abstract

Purpose: To characterize the ocular surface microbiota in regular contact lens wearers with dry eyes and assess the effectiveness of reducing bacterial load using a liposomal ozonated oil solution. Methods: This prospective, longitudinal, controlled study randomized subjects into two groups. Group A (45 subjects) received hydroxypropylmethylcellulose (HPMC, Artific®), while Group B (41 subjects) received ozonated sunflower seed oil with soybean phospholipids (OSSO, Ozonest®). Microbial communities were analyzed via DNA metabarcoding of the 16S rRNA gene, and statistical analyses (alpha and beta diversity) were performed in R. Results: Both groups predominantly harbored Staphylococcus caprae, Streptococcus oralis, and Corynebacterium spp., with OSSO and HPMC users showing distinct bacterial profiles. Alpha diversity showed no significant differences, but beta diversity revealed differences in bacterial composition between the groups. Conclusions: The results seem to indicate that the use of ozonized oil reduces the bacterial load compared to the solution used as a control.
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Keywords

Dry eyeMicrobiome ocularOzonated sunflower seed oilOzone

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Contact Lens & Anterior Eye due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2025, it was in position 14/99, thus managing to position itself as a Q1 (Primer Cuartil), in the category Ophthalmology.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-04:

  • Scopus: 3
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-04:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 12 (PlumX).
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (SANCHEZ GONZALEZ, MARIA CARMEN) .

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