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Analysis of institutional authors

Esteban, JaimeCorresponding Author

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August 4, 2025
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Review
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Clinical treatment of mycobacterial prosthetic joint infections

Publicated to: Expert Review Of Anti-Infective Therapy. 23 (9): 829-841 - 2025-09-02 23(9), DOI: 10.1080/14787210.2025.2536837

Authors:

Ortega-Portas, C; Auñon, A; Esteban, J
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Affiliations

CIBERINFEC CIBER Enfermedades Infecciosas, Madrid, Spain - Author
UAM, Fdn Jimenez Diaz Univ Hosp, Dept Orthopaed Surg, Madrid, Spain - Author
UAM, Fdn Jimenez Diaz, Dept Clin Microbiol, IIS, Madrid, Spain - Author
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Abstract

IntroductionProsthetic joint infections (PJIs) caused by mycobacteria are exceptionally rare and often underrecognized in clinical practice.Areas coveredAlthough most PJIs are due to common bacterial pathogens, Mycobacterium tuberculosis and nontuberculous mycobacteria (NTM) represent a unique subset with distinct microbiological and therapeutic challenges. The presence of biofilms further complicates their management, often requiring intensive pharmacological interventions and surgical strategies. This review analyzes over 300 reported cases of mycobacterial PJIs. The findings indicate that tuberculous PJIs typically occur as late-onset infections and are managed successfully with prolonged antituberculous therapy. In contrast, NTM PJIs - predominantly caused by rapidly growing species - are more heterogeneous in onset, resistance patterns, and treatment responses. Antibiotic regimens are often complex, species-specific, and require guidance from susceptibility testing. Therapeutic decisions often rely on expert consensus and extrapolation from pulmonary disease protocols. Surgical intervention, particularly implant removal, consistently correlates with better outcomes in both groups.Expert opinionClinicians must maintain a high index of suspicion in culture-negative PJIs or cases with atypical clinical presentations to reach a proper diagnosis. Once the diagnosis is established, a multidisciplinary approach is crucial for optimizing patient outcomes. Further research is warranted to develop evidence-based strategies for these rare but clinically demanding infections.
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Keywords

<italic>mycobacterium</italic>Antibiotic treatmenAntibiotic treatmentBacille-calmette-guerinChelonae infectioFortuitum infectionMycobacteriaMycobacteriumNontuberculous mycobacteriaPeriprosthetic tuberculosisProsthetic joint infectionPulmonary tuberculosisRapidly growing mycobacteriaShoulder arthroplastySurgeryTotal hip-arthroplastyTotal knee arthroplastyTreatmentTuberculosisTuberculosis infection

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Expert Review of Anti-Infective Therapy due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2025, it was in position 30/137, thus managing to position itself as a Q1 (Primer Cuartil), in the category Infectious Diseases.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-05:

  • WoS: 1
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-05:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 10.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 10 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: Last Author (ESTEBAN MORENO, JAIME).

the author responsible for correspondence tasks has been ESTEBAN MORENO, JAIME.

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