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Analysis of institutional authors

Gómez León NAuthor

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May 18, 2025
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Whole-body MRI Versus [18F]FDG PET/CT in Diagnosing and Monitoring Plasmacytomas: A Comparative Study.

Publicated to:Clinical nuclear medicine. (): - - 2025-05-16 (), DOI: 10.1097/RLU.0000000000005954

Authors: Gómez León N; Vicuña-Andrés I; Aguado-Bueno B; Garrido-Enjamio F; Galán-González I; Castillo-Morales V; Amor AA; Delgado Bolton RC

Affiliations

Department of Diagnostic Imaging (Radiology) and Nuclear Medicine, University Hospital San Pedro and Centre for Biomedical Research of La Rioja (CIBIR), Logroño, La Rioja, Spain. - Author
Department of Haematology, Hospital Universitario de La Princesa. - Author
Department of Nuclear Medicine, Hospital Universitario Gregorio Marañón, Madrid. - Author
Department of Radiology, Hospital Universitario Infanta Leonor. - Author
School of Medicine, Universidad Autónoma de Madrid. - Author
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Abstract

Current guidelines recommend [18F]FDG PET/CT as the preferred imaging modality for suspected extramedullary bone plasmacytomas, while whole-body magnetic resonance imaging (WB-MRI) is indicated for solitary bone plasmacytomas. Despite these recommendations, the available evidence comparing the diagnostic efficacy of both techniques remains limited. The aim of this study was to compare the diagnostic efficacy of WB-MRI and [18F]FDG PET/CT in the initial evaluation of plasmacytomas. We performed a multicenter, observational, and retrospective analysis of patients diagnosed with plasmacytoma who underwent WB-MRI and/or [18F]FDG PET/CT as part of their diagnostic workup. Lesions identified were categorized by anatomic location, and concordance between WB-MRI and [18F]FDG PET/CT findings was assessed. The McNemar test and Pearson χ2 test were used to compare detection rates between WB-MRI and [18F]FDG PET/CT. The study included 73 patients (33 men) recruited between 2012 and 2023, age range 30-94 years (mean 63.4 ± 12.2 y). Of these, 56 patients underwent both diagnostic tests. Diagnoses revealed solitary plasmacytoma in 16 patients, concurrent multiple myeloma (MM) and plasmacytoma in 18 patients, and plasmacytoma in 22 patients with a prior MM history. Out of the 56 plasmacytomas, 40 were osseous and 16 were extramedullary. WB-MRI detected 98.2% of plasmacytomas compared with 83.9% for [18F]FDG PET/CT, with a statistically significant difference of OR 9 (95% CI: 1.2-394.5), P=0.021. Concordance was very high for osseous plasmacytomas but moderate for extramedullary plasmacytomas. These findings suggest WB-MRI is an alternative to [18F]FDG PET/CT for detecting plasmacytomas. A comprehensive clinical and radiologic assessment is essential for the optimal evaluation of patients with plasmacytoma.

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Quality index

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-07-05:

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 2.5.
  • The number of mentions on the social network X (formerly Twitter): 2 (Altmetric).

Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (GOMEZ LEON, MŞ DE LAS NIEVES) .