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Ana Beatriz Gago VeigaAuthor

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Headache in patients with inflammatory bowel disease: migraine prevalence according to the migraine screening-questionnaire (ms-q) and headache characteristics

Publicated to:Gastroenterologia y Hepatologia. 47 (1): 63 - 71 - 2024-01-01 47(1), DOI:

Authors: Alicia González Martínez; Inés Muro; Sofía Quintas; María Chaparro Sánchez; Javier Pérez Gisbert; Ancor Sanz García; María José Casanova González; Cristina Rubín de Célix Vargas; José Vivancos Mora; Ana Beatriz Gago Veiga

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Abstract

Background The gut-brain axis describes a complex bidirectional association between neurological and gastrointestinal (GI) disorders. In patients with migraine, GI comorbidities are common. We aimed to evaluate the presence of migraine among patients with inflammatory bowel disease (IBD) according to Migraine Screen-Questionnaire (MS-Q) and describe the headache characteristics compared to a control group. Additionally, we explored the relationship between migraine and IBD severities. Methods We performed a cross-sectional study through an online survey including patients from the IBD Unit at our tertiary hospital. Clinical and demographic variables were collected. MS-Q was used for migraine evaluation. Headache disability scale HIT-6, anxiety-depression scale HADS, sleep scale ISI, and activity scale Harvey–Bradshaw and Partial Mayo scores were also included. Results We evaluated 66 IBD patients and 47 controls. Among IBD patients, 28/66 (42%) were women, mean age 42 years and 23/66 (34.84%) had ulcerative colitis. MS-Q was positive in 13/49 (26.5%) of IBD patients and 4/31 (12.91%) controls (p = 0.172). Among IBD patients, headache was unilateral in 5/13 (38%) and throbbing in 10/13 (77%). Migraine was associated with female sex (p = 0.006), lower height (p = 0.003) and weight (p = 0.002), anti-TNF treatment (p = 0.035). We did not find any association between HIT-6 and IBD activity scales scores. Conclusions Migraine presence according to MS-Q could be higher in patients with IBD than controls. We recommend migraine screening in these patients, especially in female patients with lower height and weight and anti-TNF treatment.

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