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Analysis of institutional authors

Gonzalez-Peramato, PilarAuthor

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July 21, 2024
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Clinical, Pathological Characteristics and Progression of Urothelial Bladder Cancer in Young Adult Patients. Our Experience and Literature Review

Publicated to: Archivos Españoles De Urología. 77 (5): 463-470 - 2024-06-01 77(5), DOI: 10.56434/j.arch.esp.urol.20247705.65

Authors:

González, SP; Heredia-Soto, V; de Francisco, MG; Pérez-Fernandez, E; Casans-Francés, R; Rodríguez, VD; Sabio, MM; González-Peramato, P
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Affiliations

Alcorcon Fdn Univ Hosp, Res Unit, Madrid 28922, Spain - Author
Autonomous Univ Madrid, Dept Pathol Anat, Madrid 28049, Spain - Author
Carlos III Hlth Inst, Ctr Biomed Res Canc Network CIBERONC, Madrid 28029, Spain - Author
Hosp La Paz Inst Hlth Res IdiPAZ, Cellular Engn Lab, Madrid 28046, Spain - Author
Hosp La Paz Inst Hlth Res IdiPAZ, Mol Pathol & Therapeut Targets Grp, Madrid 28046, Spain - Author
Hosp La Paz Inst Hlth Res IdiPAZ, Translat Oncol Res Lab, Madrid 28046, Spain - Author
Infanta Elena Univ Hosp, Dept Anesthesia & Pain Med, Madrid 28342, Spain - Author
Infanta Leonor Univ Hosp, Dept Neurol, Madrid 28031, Spain - Author
La Paz Univ Hosp, Dept Pathol, Madrid 28046, Spain - Author
La Paz Univ Hosp, Dept Urol, Madrid 28046, Spain - Author
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Abstract

Background: Bladder cancer is highly prevalent even though its incidence is considerably lower in patients younger than 40 years, thus raising the issue of the influence of age at diagnosis on the natural history of this disease. This study aimed to evaluate the characteristics and progression of young patients with urothelial bladder carcinoma with at least 10 years of follow-up and to compare the results with those of previously reported studies. Material and Methods: A retrospective study between 1990 and 2007 was conducted. The medical records and tissue samples of patients with urothelial bladder tumours were reviewed, and patients with a first diagnosis of urothelial carcinoma of the bladder at age 40 years or younger were selected. Their clinical and pathological data and disease-free survival were analysed. Results: This study included 43 patients, with a median follow-up of 152 months (interquartile range (IQR): 96-222) and a mean age at diagnosis of 34 years (SD: 4.6). Thirty-five patients (81.4%) had non-muscle invasive tumours at diagnosis, and 53.5%, 27.9% and 18.6% had tumour grades of G1, G2 and G3, respectively. Fifteen patients (34.9%) experienced recurrence, and eight (18.6%) progressed. At 24 and 60 months, the recurrence-free survival rates were 84.8% (95% confidence interval (CI): 69.2%-92.9%) and 68.9% (95% CI: 51.7%-81%), respectively, and the progression-free survival rates were 94.9% (95% CI: 81%-98.7%) and 92.2% (95% CI: 77.8%-97.4%), respectively. Conclusions: Bladder cancer is an uncommon disease in young patients. In most cases, it consists of non-muscle-invasive tumours, with a low rate of recurrence and progression. The prognosis is based on the tumour's characteristics and not on the patient's age.
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Keywords

AgeBladderNatural-historyOldPatients lessPersonal historRisThan 40 yearsTransitional-cell-carcinomaTumorsUrinary-bladderUrothelial carcinomaYoung

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Archivos Españoles de Urología, and although the journal is classified in the quartile Q4 (Agencia WoS (JCR)), its regional focus and specialization in Urology & Nephrology, give it significant recognition in a specific niche of scientific knowledge at an international level.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-05:

  • WoS: 2
  • Scopus: 2
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-05:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 3.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 3 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: Last Author (GONZALEZ-PERAMATO GUTIERREZ, MARIA DEL PILAR).

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Awards linked to the item

Acknowledgment This study was approved by the Ethics Committee of La Paz University Hospital (institution review board num- ber: PI -5332) and was performed in accordance with the principles of the Declaration of Helsinki. All participants signed an informed consent form prior to surgery procedure.
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