RUIZ ORTEGA, MARTA
iMarina ID: 04-260902Códigos de identificación
Grupo
Biología Molecular y Celular en Patología Renal y Vascular.. Universidad Autónoma de Madrid. Ciudad Universitaria de Cantoblanco. Madrid. 28049
Departamento Universitario
Medicina. Universidad Autónoma de Madrid. Ciudad Universitaria de Cantoblanco. Madrid. 28049
Centro
Facultad de Medicina. Universidad Autónoma de Madrid. Ciudad Universitaria de Cantoblanco. Madrid. 28049
Timeline
enero de 1996
Doctorado: Doctor en Ciencias Químicas
Universidad Autónoma de Madrid
junio de 1991
Titulado superior / Grado: Licenciado en Ciencias Químicas. Especialidad de Bioquímica.
Universidad Complutense de Madrid
Timeline
febrero de 2019
Coordinador/a
Universidad Autónoma de Madrid. Biología Molecular y Celular en Patología Renal y Vascular.
2019 -
junio de 2008
MEDICINA DELEG. DECANATO ASUNTOS INVEST.TRASLACIONAL
Universidad Autónoma de Madrid
2008 - 2011
junio de 2008
DELE. DECANO MEDICINA ASUNTOS INVEST.TRASLACIONAL
Universidad Autónoma de Madrid
2008 - 2011
diciembre de 2007
Profesor Contratado Doctor LOU
Universidad Autónoma de Madrid. Medicina
2007 -
abril de 2003
Ramón y Cajal. Medicina
Universidad Autónoma de Madrid
2003 - 2007
marzo de 2000
Research Professor
Freie Universitat, CHARITE, Berlin, Alemania
2000 - 2006
enero de 1999
Freie Universitat, MOLOGEN, Berlin, Alemania
Freie Universitat, MOLOGEN, Berlin, Alemania
1999 - 1999
enero de 1999
Postdoctoral researcher
Freie Universitat, MOLOGEN, Berlin, Alemania
1999 -
enero de 1997
Postdoctoral Researcher Beca CAM
Freie Universitat, MOLOGEN, Berlin, Alemania
1997 -
enero de 1997
Postdoctoral Researcher Beca CAM
Fundación Jiménez Díaz
1997 - 2000
enero de 1996
Postdoctoral researcher
VANDERBILT University. TENNESSE. USA
1996 - 1996
enero de 1994
Beca FPU
Universidad Autónoma de Madrid
1994 - 1996
enero de 1992
Beca Fundación Conchita Rábago
Fundación Jiménez Díaz
1992 - 1994
enero de 1991
Student Researcher
National Heart and Lung Institute. Biochemistry Unit. Imperial College. University of London
1991 - 1991
Reconocimientos Docentes
Quinquenios
4
Año último Quinquenio: 2018
Reconocimientos Investigación
Sexenios
4
Año último Sexenio: 2015
Publicaciones en Altmetrics
| 2020 | MiR-9-5p protects from kidney fibrosis by metabolic reprogramming | |
| 2020 | Design and optimization strategies for the development of new drugs that treat c... | |
| 2019 | Interleukin 17A Participates in Renal Inflammation Associated to Experimental an... | |
| 2019 | PGC-1? deficiency causes spontaneous kidney inflammation and increases the sever... | |
| 2019 | Interleukin-17A blockade reduces albuminuria and kidney injury in an accelerated... | |
| 2019 | Signal Integration and Transcriptional Regulation of the Inflammatory Response M... | |
| 2019 | Bromodomain and extraterminal proteins as novel epigenetic targets for renal dis... | |
| 2019 | Gremlin, A Potential Urinary Biomarker of Anca-Associated Crescentic Glomerulone... | |
| 2019 | Wilms Tumor 1b Expression Defines a Pro-regenerative Macrophage Subtype and Is R... | |
| 2018 | Gremlin and renal diseases: Ready to jump the fence to clinical utility? | |
| 2018 | Impact of altered intestinal microbiota on chronic kidney disease progression | |
| 2018 | Targeting epigenetic DNA and histone modifications to treat kidney disease | |
| 2018 | Gremlin activates the Notch pathway linked to renal inflammation. | |
| 2018 | CCL20 blockade increases the severity of nephrotoxic folic acid-induced acute ki... | |
| 2018 | Could the Notch signaling pathway be a potential therapeutic option in renal dis... | |
| 2018 | Connective tissue growth factor induces renal fibrosis via epidermal growth fact... | |
| 2018 | Targeting of regulated necrosis in kidney disease | |
| 2018 | Could Notch signaling pathway be a potential therapeutic option in renal disease... | |
| 2018 | Epigenetic modification mechanisms involved in inflammation and fibrosis in rena... | |
| 2018 | Role of epidermal growth factor receptor (EGFR) and its ligands in kidney inflam... | |
| 2018 | Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Poten... | |
| 2018 | Branched-chain amino acids promote endothelial dysfunction through increased rea... | |
| 2018 | Targeting inflammation in diabetic nephropathy: a tale of hope | |
| 2018 | TWEAK and RIPK1 mediate a second wave of cell death during AKI. | |
| 2018 | Targeting of regulated necrosis in kidney disease | |
| 2017 | Differential effect of quercetin on cisplatin-induced toxicity in kidney and tum... | |
| 2017 | Translational science in chronic kidney disease. | |
| 2017 | Inhibition of Bromodomain and Extraterminal Domain Family Proteins Ameliorates E... | |
| 2017 | MXRA5 is a TGF-β1-regulated human protein with anti-inflammatory and anti-fibrot... | |
| 2017 | Atrasentan for the treatment of diabetic nephropathy. | |
| 2017 | High concentration of branched-chain amino acids promotes oxidative stress, infl... | |
| 2017 | Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid-Induced... | |
| 2017 | 2017 update on the relationship between diabetes and colorectal cancer: epidemio... | |
| 2017 | Deferasirox-induced iron depletion promotes BclxL downregulation and death of pr... | |
| 2017 | BET Proteins: An Approach to Future Therapies in Transplantation | |
| 2017 | Bcl3: a regulator of NF-κB inducible by TWEAK in acute kidney injury with anti-i... | |
| 2016 | Oxidative stress in disease and aging: Mechanisms and therapies | |
| 2016 | Downregulation of kidney protective factors by inflammation: role of transcripti... | |
| 2016 | Calcineurin inhibitors cyclosporine A and tacrolimus induce vascular inflammatio... | |
| 2016 | Non-canonical NF kappa B activation promotes chemokine expression in podocytes | |
| 2016 | The inflammatory cytokine TWEAK decreases PGC-1alpha expression and mitochondria... | |
| 2016 | Histone lysine-crotonylation in acute kidney injury | |
| 2016 | Targeting inflammation in diabetic kidney disease: early clinical trials | |
| 2016 | Out of the TWEAKlight: Elucidating the Role of Fn14 and TWEAK in Acute Kidney In... | |
| 2016 | Angiotensin receptors and β-catenin regulate brain endothelial integrity in mala... | |
| 2015 | Up-regulation of the kinin B2 receptor pathway modulates the TGF-β/Smad signalin... | |
| 2015 | Lyso-Gb3 activates Notch1 in human podocytes | |
| 2015 | Biocompatibility Reduces Inflammation-Induced Apoptosis in Mesothelial Cells Exp... | |
| 2015 | Association between the IL17RA rs4819554 polymorphism and reduced renal filtrati... | |
| 2015 | Translational value of animal models of kidney failure | |
| 2015 | Angiotensin II Moderately Decreases Plasmodium Infection and Experimental Cerebr... | |
| 2015 | TNF-related weak inducer of apoptosis (TWEAK) regulates junctional proteins in t... | |
| 2015 | Tubular overexpression of gremlin in transgenic mice aggravates renal damage in ... | |
| 2015 | Targeting of Gamma-Glutamyl-Cysteine Ligase by miR-433 Reduces Glutathione Biosy... | |
| 2015 | Paricalcitol inhibits aldosterone-induced proinflammatory factors by modulating ... | |
| 2015 | GREMLIN REGULATES RENAL INFLAMMATION VIA VASCULAR ENDOTHELIAL GROWTH FACTOR RECE... | |
| 2015 | TUBULAR OVEREXPRESSION OF GREMLIN IN TRANSGENIC MICE AGGRAVATES RENAL DAMAGE IN ... | |
| 2015 | PARICALCITOL INHIBITED ALDOSTERONE-INDUCED PROINFLAMMATORY FACTORS BY MODULATING... | |
| 2015 | MCP-2/CCR8 AXIS IS ACTIVATED IN EXPERIMENTAL RENAL AND VASCULAR INFLAMMATION | |
| 2015 | PARICALCITOL EXERTS ANTI-INFLAMMATORY EFFECTS IN EXPERIMENTAL MODELS OF RENAL DA... | |
| 2015 | T helper 17/regulatory t cell balance and experimental models of peritoneal dial... | |
| 2015 | Gremlin regulates renal inflammation via the vascular endothelial growth factor ... | |
| 2015 | Horizon 2020 in Diabetic Kidney Disease: The Clinical Trial Pipeline for Add-On ... | |
| 2015 | The C-Terminal Module IV of Connective Tissue Growth Factor, Through EGFR/Nox1 S... | |
| 2015 | Angiotensin II, via angiotensin receptor type 1/nuclear factor-κB activation, ca... | |
| 2015 | Albumin-induced apoptosis of tubular cells is modulated by BASP1 | |
| 2015 | TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module o... | |
| 2015 | Designing drugs that combat kidney damage | |
| 2014 | Macrophages and Recently Identified Forms of Cell Death | |
| 2014 | Tubular overexpression of gremlin induces renal damage susceptibility in mice | |
| 2014 | Endogenous NAMPT dampens chemokine expression and apoptotic responses in stresse... | |
| 2014 | Translational study of the Notch pathway in hypertensive nephropathy | |
| 2014 | Paricalcitol Reduces Peritoneal Fibrosis in Mice through the Activation of Regul... | |
| 2014 | TWEAK Promotes Peritoneal Inflammation | |
| 2014 | 3,4-DGE is cytotoxic and decreases HSP27/HSPB1 in podocytes | |
| 2014 | Integrin-linked kinase plays a key role in the regulation of angiotensin II-indu... | |
| 2014 | Soluble co-signaling molecules predict long-term graft outcome in kidney-transpl... | |
| 2014 | IL-17A is a novel player in dialysis-induced peritoneal damage | |
| 2014 | TWEAK and the progression of renal disease: Clinical translation | |
| 2014 | Gremlin Activates the Smad Pathway Linked to Epithelial Mesenchymal Transdiffere... | |
| 2014 | Unilateral ureteral obstruction: Beyond obstruction | |
| 2014 | Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and kidney disease | |
| 2013 | Fn14 in podocytes and proteinuric kidney disease | |
| 2013 | The C-terminal module IV of connective tissue growth factor is a novel immune mo... | |
| 2013 | TWEAK transactivation of the epidermal growth factor receptor mediates renal inf... | |
| 2013 | Connective tissue growth factor is a new ligand of epidermal growth factor recep... | |
| 2013 | TNF-related weak inducer of apoptosis (TWEAK) promotes kidney fibrosis and Ras-d... | |
| 2013 | Osteoprotegerin in Exosome-Like Vesicles from Human Cultured TubularCells and Ur... | |
| 2013 | A Polymeric Nanomedicine Diminishes Inflammatory Events in Renal TubularCells | |
| 2012 | Inflammatory Cytokines and Survival Factors from Serum ModulateTweak-Induced Apo... | |
| 2012 | Angiotensin II Contributes to Renal Fibrosis Independently of NotchPathway Activ... | |
| 2012 | Pharmacological modulation of peritoneal injury induced by dialysis fluids: is i... | |
| 2012 | GSK3, Snail, and Adhesion Molecule Regulation by Cyclosporine A in RenalTubular ... | |
| 2012 | TWEAK (tumor necrosis factor-like weak inducer of apoptosis) activatesCXCL16 exp... | |
| 2012 | HSP27/HSPB1 as an adaptive podocyte antiapoptotic protein activated byhigh gluco... | |
| 2012 | Association between a common KCNJ11 polymorphism (rs5219) and new-onset posttran... | |
| 2012 | Gremlin Is a Downstream Profibrotic Mediator of Transforming GrowthFactor-Beta i... | |
| 2012 | Acute kidney injury transcriptomics unveils a relationship between inflammation ... | |
| 2011 | The Inflammatory Cytokines TWEAK and TNF alpha Reduce Renal Klotho Expression th... | |
| 2011 | Glutamatergic Signaling Maintains the Epithelial Phenotype of ProximalTubular Ce... | |
| 2011 | KCNQ1 gene variants and risk of new-onset diabetes in tacrolimus-treated renal-t... | |
| 2011 | Tenofovir nephrotoxicity: 2011 update | |
| 2011 | Mitochondrial DNA and TFAM gene variation in early-onset myocardial infarction: ... | |
| 2011 | Globotriaosylsphingosine actions on human glomerular podocytes:implications for ... | |
| 2011 | TWEAK and the Kidney: the Dual Role of a Multifunctional Cytokine | |
| 2010 | BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal... | |
| 2010 | Tyrphostins as Potential Therapeutic Agents for Acute Kidney Injury | |
| 2010 | BASP1 Promotes Apoptosis in Diabetic Nephropathy | |
| 2010 | Statins Inhibit Angiotensin II/Smad Pathway and Related VascularFibrosis, by a T... | |
| 2010 | NF-kappa B in Renal Inflammation | |
| 2010 | Regulation of vascular and renal cells by common mediators in health and disease... | |
| 2010 | TWEAK Activates the Non-Canonical NF kappa B Pathway in Murine RenalTubular Cell... | |
| 2010 | TNF Superfamily: A Growing Saga of Kidney Injury Modulators | |
| 2010 | Functional polymorphisms in the CYP3A4, CYP3A5, and CYP21A2 genes in the risk fo... | |
| 2010 | PPAR-gamma agonist rosiglitazone protects peritoneal membrane from dialysis flui... | |
| 2009 | Tweak induces proliferation in renal tubular epithelium: a role inuninephrectomy... | |
| 2009 | Transcriptomics illustrate a deadly TRAIL to diabetic nephropathy | |
| 2009 | A Nanoconjugate Apaf-1 Inhibitor Protects Mesothelial Cells from Cytokine-Induce... | |
| 2009 | CTGF Promotes Inflammatory Cell Infiltration of the Renal Interstitiumby Activat... | |
| 2009 | Angiotensin-(1-7) and the G Protein-Coupled Receptor Mas Are Key Playersin Renal... | |
| 2009 | Atorvastatin attenuates angiotensin II-induced inflammatory actions in the liver | |
| 2009 | The MIF Receptor CD74 in Diabetic Podocyte Injury | |
| 2009 | El factor de crecimiento de tejido conectivo (CTGF): factor clave en el inicio y... | |
| 2009 | Parathyroid Hormone-Related Protein Promotes Epithelial-MesenchymalTransition | |
| 2009 | Atorvastatin Prevents Angiotensin II-Induced Vascular Remodeling and Oxidative S... | |
| 2008 | Gremlin: A novel mediator of epithelial mesenchymal transition andfibrosis in ch... | |
| 2008 | Inhibitory effect of interleukin-1 beta on angiotensin II-inducedconnective tiss... | |
| 2008 | Parathyroid hormone-related protein promotes inflammation in the kidneywith an o... | |
| 2008 | Essential Role of TGF-beta/Smad Pathway on Statin Dependent VascularSmooth Muscl... | |
| 2008 | Pharmacological modulation of epithelial mesenchymal transition causedby angiote... | |
| 2008 | Mechanisms of renal apoptosis in health and disease | |
| 2008 | Angiotensin II activates the Smad pathway during epithelial mesenchymaltransdiff... | |
| 2008 | A slit in podocyte death | |
| 2008 | The cytokine TWEAK modulates renal tubulointerstitial inflammation | |
| 2008 | Mitochondrial transcription factors TFA, TFB1 and TFB2: A search for DNAvariants... | |
| 2008 | 3,4-dideoxyglucosone-3-ene as a mediator of peritoneal demesothelization | |
| 2007 | HMG-CoA reductase inhibitors decrease angiotensin-II-induced vascularfibrosis - ... | |
| 2007 | Expression of gremlin, a bone morphogenetic protein antagonist, inglomerular cre... | |
| 2007 | Anti-inflammatory actions of quinapril | |
| 2007 | TGF-beta signaling in vascular fibrosis | |
| 2007 | Interactions between aldosterone and connective tissue growth factor invascular ... | |
| 2007 | The regulation of the inflammatory response through nuclear factor-kappaB pathwa... | |
| 2007 | Pleiotropic effects of telmisartan in diabetic patients | |
| 2007 | Role of connective tissue growth factor in vascular and renal damageassociated w... | |
| 2007 | Role of connective tissue growth factor in vascular damage associated with hyper... | |
| 2006 | Role of parathyroid hormone-related protein in tubulointerstitialapoptosis and f... | |
| 2006 | Renal and vascular hypertension-induced inflammation: role ofangiotensin II | |
| 2006 | Angiotensin II: a key factor in the inflammatory and fibrotic responsein kidney ... | |
| 2005 | Angiotensin II regulates vascular endothelial growth factor via hypoxia-inducibl... | |
| 2005 | The Rho-kinase pathway regulates angiotensin II-induced renal damage | |
| 2005 | Suppressors of cytokine signaling regulate angiotensin II-activated janus kinase... | |
| 2005 | Angiotensin II and reactive oxygen species | |
| 2005 | Reactive oxygen species-mediated signaling pathways in angiotensinII-induced MCP... | |
| 2005 | Endothelin-1, via ETA receptor and independently of transforming growthfactor-be... | |
| 2005 | Angiotensin II activates the Smad pathway in vascular smooth musclecells by a tr... | |
| 2005 | Angiotensin IV activates the nuclear transcription factor-¿B and related proinfl... | |
| 2004 | Angiotensin II activates the Smad signalling pathway: Role in vascular fibrosis | |
| 2004 | RhoA/Rho-kinase pathway regulates Angiotensin II-induced connective tissue growt... | |
| 2004 | Interleukin-1beta inhibits connective tissue growth factor and fibronectin produ... | |
| 2004 | NF-kappa B activation and overexpression of regulated genes in humandiabetic nep... | |
| 2004 | Angiotensin II, via AT(1) and AT(2) receptors and NF-kappa B pathway,regulates t... | |
| 2004 | Statins to prevent cardiovascular events in hypertensive patients. TheASCOT-LLA ... | |
| 2003 | Molecular mechanisms of angiotensin II-induced vascular injury | |
| 2003 | Angiotensin II increases connective tissue growth factor in the kidney | |
| 2003 | Effect of simultaneous blockade of AT1 and AT2 receptors on the NF kappaB pathwa... | |
| 2003 | Renin-angiotensin system activation and interstitial inflammation inhuman diabet... | |
| 2003 | Renal angiotensin II up-regulation and myofibroblast activation in humanmembrano... | |
| 2003 | Renal expression of angiotensin type 2 (AT2) receptors during kidneydamage | |
| 2003 | Connective tissue growth factor is a mediator of angiotensin II-inducedfibrosis | |
| 2003 | Inflammation and angiotensin II | |
| 2003 | Angiotensin II, the immune system and renal diseases: another road for RAS? | |
| 2002 | Angiotensin II increases parathyroid hormone-related protein (PTHrP) andthe type... | |
| 2002 | Susceptibility to T cell-mediated injury in immune complex disease is linked to ... | |
| 2002 | Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokin... | |
| 2001 | Role of the renin-angiotensin system in vascular diseases - Expandingthe field | |
| 2001 | Angiotensin II and renal fibrosis | |
| 2001 | Angiotensin II activates nuclear transcription factor-kappa B in aorta of normal... | |
| 2001 | Systemic infusion of angiotensin II into normal rats activates nuclearfactor-kap... | |
| 2001 | Proinflammatory actions of angiotensins | |
| 2000 | Angiotensin II activates nuclear transcription factor kappa B throughAT(1) and A... | |
| 2000 | Angiotensin III increases MCP-1 and activates NF-kappa B and AP-1 incultured mes... | |
| 2000 | Regulation of matrix proteins and impact on vascular structure | |
| 1998 | Overexpression of extracellular matrix proteins in renal tubulointerstitial cell... | |
| 1998 | Angiotensin III up-regulates genes involved in kidney damage inmesangial cells a... | |
| 1997 | Angiotensin-converting enzyme inhibition prevents arterial nuclear factor-κB act... | |
| 1997 | Angiotensin II modulates cell growth-related events and synthesis of matrix prot... | |
| 1996 | Expression of leucocyte chemoattractants by interstitial renalfibroblasts: Up-re... | |
| 1996 | Effects and interactions of endothelin-1 and angiotensin II on matrixprotein exp... | |
| 1995 | Cyclosporin A (CsA) modulates the glomerular production of inflammatorymediators... | |
| 1995 | ACE inhibition reduces proteinuria, glomerular lesions and extracellular matrix ... | |
| 1995 | Potential factors governing extracellular matrix production by mesangial cells: ... |
Temáticas más frecuentes
Temáticas
Proyectos participados
Dirección y participación en proyectos
IP
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Grupos, Redes
Biología Molecular y Celular en Patología Renal y Vascular.
Actividad docente
Tesis Dirigidas
14
Centros
Universidad Autónoma de Madrid
Asignatura / Curso
Colaboración institucional últimos 5 años
