Timeline
enero de 1974
Doctorado: Doctor/a
Timeline
marzo de 1986
Catedrático de universidad. Biología Molecular
Universidad Autónoma de Madrid
   1986 - 2019
enero de 1985
Profesor Titular Universidad. Biología Molecular
Universidad Autónoma de Madrid
   1985 - 1986
julio de 1975
Colaborador Científico. Biología Molecular
Universidad Autónoma de Madrid
   1975 - 1978
Reconocimientos Docentes
Quinquenios
6
Año último Quinquenio: 2001
Reconocimientos Investigación
Sexenios

6
Año último Sexenio: 2007
Publicaciones en Altmetrics
2020 | Polymicrobial Infections and Neurodegenerative Diseases | |
2019 | A viral RNA motif involved in signaling the initiation of translation on non-AUG... | |
2019 | Brain Microbiota in Huntington’s Disease Patients | |
2019 | Searching for Bacteria in Neural Tissue From Amyotrophic Lateral Sclerosis | |
2019 | System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus I... | |
2018 | Human and Microbial Proteins From Corpora Amylacea of Alzheimer's Disease | |
2018 | Mechanisms of virus-induced cell toxicity: A general overview | |
2018 | The Regulation of Translation in Alphavirus-Infected Cells. | |
2018 | Multiple sclerosis and mixed microbial infections. Direct identification of fung... | |
2018 | Infection of Fungi and Bacteria in Brain Tissue From Elderly Persons and Patient... | |
2018 | The Initiation Factors eIF2, eIF2A, eIF2D, eIF4A, and eIF4G Are Not Involved in ... | |
2017 | Alzheimer's Disease and Fungal Infection | |
2017 | Identification of Fungal Species in Brain Tissue from Alzheimer's Disease by Nex... | |
2017 | Fungal infection in neural tissue of patients with amyotrophic lateral sclerosis... | |
2017 | Polymicrobial Infections In Brain Tissue From Alzheimer's Disease Patients. | |
2017 | Translation of Sindbis Subgenomic mRNA is Independent of eIF2, eIF2A and eIF2D | |
2016 | Influence of glutathione availability on cell damage induced by human immunodefi... | |
2016 | Corpora Amylacea of Brain Tissue from Neurodegenerative Diseases Are Stained wit... | |
2016 | A Viral mRNA Motif at the 3 '-Untranslated Region that Confers Translatability i... | |
2016 | Fungal Enolase, beta-Tubulin, and Chitin Are Detected in Brain Tissue from Alzhe... | |
2015 | Inhibition of host protein synthesis by Sindbis virus: correlation with viral RN... | |
2015 | Different Brain Regions are Infected with Fungi in Alzheimer's Disease | |
2015 | Impact of Vesicular Stomatitis Virus M Proteins on Different Cellular Functions | |
2015 | Evidence for fungal infection in cerebrospinal fluid and brain tissue from patie... | |
2015 | Direct visualization of fungal infection in brains from patients with Alzheimer'... | |
2015 | Initiation codon selection is accomplished by a scanning mechanism without cruci... | |
2015 | Differential action of pateamine A on translation of genomic and subgenomic mRNA... | |
2015 | Cerebrospinal Fluid from Alzheimer's Disease Patients Contains Fungal Proteins a... | |
2015 | Viroporins: Structures and functions beyond cell membrane permeabilization | |
2014 | L protease from foot and mouth disease virus confers eIF2-independent translatio... | |
2014 | Aplidin: first in class compound targeting EEF1A in tumor cells | |
2014 | Alzheimer's disease and disseminated mycoses | |
2014 | Fungal infection in patients with Alzheimer's disease | |
2014 | Corrigendum: Participation of eIF4F complex in Junin virus infection: Blockage o... | |
2013 | Poliovirus 2A Protease Triggers a Selective Nucleo-Cytoplasmic Redistribution of... | |
2013 | Requirements for eIF4A and eIF2 during translation of Sindbis virus subgenomic m... | |
2013 | Participation Of Eif4F Complex In Junin Virus Infection: Blockage Of Eif4E Does ... | |
2013 | Fungal infection in cerebrospinal fluid from some patients with multiple scleros... | |
2013 | Translation of viral mRNAs that do not require eIF4E is blocked by the inhibitor... | |
2013 | Phosphorylation of eIF2 alpha is responsible for the failure of the picornavirus... | |
2012 | Translation Directed by Hepatitis A Virus IRES in the Absence of Active eIF4F Co... | |
2012 | Membrane-active peptides derived from picornavirus 2B viroporin | |
2012 | Viroporins: Structure and biological functions | |
2012 | A non-infectious cell-based phenotypic assay for the assessment of HIV-1 suscept... | |
2011 | Translation without eIF2 Promoted by Poliovirus 2A Protease | |
2011 | Alternative splicing, a new target to block cellular gene expression by poliovir... | |
2011 | Translation of Viral mRNA without Active eIF2: The Case of Picornaviruses | |
2011 | The Multifaceted Poliovirus 2A Protease: Regulation of Gene Expression by Picorn... | |
2011 | Membrane integration of poliovirus 2B viroporin | |
2011 | Fungal infection in a patient with multiple sclerosis | |
2011 | Functional impairment of eIF4A and elF4G factors correlates withinhibition of in... | |
2010 | Cell permeabilization by poliovirus 2B viroporin triggers bystander permeabiliza... | |
2010 | A peptide based on the pore-forming domain of pro-apoptotic poliovirus2B viropor... | |
2010 | Association between multiple sclerosis and Candida species: evidencefrom a case-... | |
2010 | Translation Driven by Picornavirus IRES Is Hampered from Sindbis Virus Replicons... | |
2009 | HIV-1 protease inhibits cap-and poly(A)-dependent translation upon eIF4GI and PA... | |
2009 | Regulation of Host Translational Machinery by African Swine Fever Virus | |
2009 | RNA nuclear export is blocked by poliovirus 2A protease and is concomitant with ... | |
2009 | Translation of mRNAs from Vesicular Stomatitis Virus and Vaccinia Virus Is Diffe... | |
2009 | Dual Mechanism for the Translation of Subgenomic mRNA from Sindbis Virus in Infe... | |
2008 | Functional and structural characterization of 2B viroporin membranolyticdomains | |
2008 | Viroporins from RNA viruses induce caspase-dependent apoptosis | |
2008 | Fungal infection in patients with serpiginous choroiditis or acute zonaloccult o... | |
2007 | Viral translation is coupled to transcription in sindbis virus-infected cells | |
2007 | Plasma membrane-porating domain in poliovirus 2B protein. A shortpeptide mimics ... | |
2007 | Evolution of antibody response and fungal antigens in the serum of apatient infe... | |
2007 | Differential inhibition of cellular and Sindbis virus translation by brefeldin A | |
2007 | Attachment and entry of Candida famata in monocytes and epithelial cells | |
2006 | Translational resistance of late alphavirus mRNA to eIF2¿ phosphorylation: a str... | |
2006 | HIV protease cleaves poly(A)-binding protein | |
2006 | Differential cleavage of eIF4GI and eIF4GII in mammalian cells - Effects on tran... | |
2006 | Translation of Sindbis virus 26 S mRNA does not require intact eukariotic initia... | |
2006 | Antiviral effect of the mammalian translation initiation factor 2 alpha kinase G... | |
2005 | Viroporin activity of murine hepatitis virus E protein | |
2005 | Regulation of HIV-1 env mRNA translation by Rev protein | |
2005 | Requirement of the vesicular system for membrane permeabilization by Sindbis vir... | |
2005 | Involvement of HIV-1 protease in virus-induced cell killing | |
2005 | Isolation of Candida famata from a patient with acute zonal occult outer retinop... | |
2004 | Individual expression of poliovirus 2A(pro) and 3C(pro) inducesactivation of cas... | |
2004 | Membrane-permeabilizing motif in Semliki forest virus E1 glycoprotein | |
2003 | Cell killing by HIV-1 protease | |
2003 | Individual expression of Sindbis virus glycoproteins. E1 alone promotes cell fus... | |
2003 | Interfacial domains in Sindbis virus 6K protein - Detection and functional chara... | |
2003 | The eukaryotic translation initiation factor 4GI is cleaved by different retrovi... | |
2003 | Cleavage of eIF4G by HIV-1 protease: Effects on translation | |
2003 | Viroporins | |
2003 | Mechanisms of membrane permeabilization by picornavirus 2B viroporin | |
2002 | Viroporin-mediated membrane permeabilization - Pore formation bynonstructural po... | |
2002 | Antiviral activity of seven iridoids, three saikosaponins and one phenylpropanoi... | |
2001 | Sindbis virus variant with a deletion in the 6K gene shows defects in glycoprote... | |
2001 | Antipoliovirus flavonoids from Psiadia dentata | |
2001 | Entry of poliovirus into cells is blocked by valinomycin andconcanamycin A | |
2001 | Human immunodeficiency virus type 1 VPU protein affects Sindbis virus glycoprote... | |
2001 | HIV-1 protease cleaves eukaryotic initiation factor 4G and inhibits cap-dependen... | |
2000 | Search for antiviral activity in higher plant extracts | |
2000 | Poliovirus induces apoptosis in the human U937 promonocytic cell line | |
2000 | A stable HeLa cell line that inducibly expresses poliovirus 2A(pro):Effects on c... | |
2000 | Poliovirus protease 3C(pro) kills cells by apoptosis | |
2000 | Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protei... | |
2000 | The amino-terminal nine amino acid sequence of poliovirus capsid VP4 protein is ... | |
1999 | Antiviral activity of some South American medicinal plants | |
1999 | Genetic selection of poliovirus 2A(pro)-binding peptides | |
1999 | Antiviral activity of Bolivian plant extracts | |
1999 | Cleavage of eukaryotic translation initiation factor 4G by exogenously added hyb... | |
1998 | Mutational analysis of poliovirus 2A(pro) - Distinct inhibitory functions of 2A(... | |
1998 | Poliovirus 2A proteinase cleaves directly the eIF-4G subunit of eIF-4F complex | |
1998 | Effect of nitric oxide on poliovirus infection of two human cell lines | |
1998 | The human immunodeficiency virus type 1 Vpu protein enhances membrane permeabili... | |
1998 | Co-expression of human elF-4G and poliovirus 2A(pro) in Saccharomyces cerevisiae... | |
1998 | Genetic analysis of poliovirus protein 3A: Characterization of a non-cytopathic ... | |
1998 | Identification of regions of poliovirus 2BC protein that are involved in cytotox... | |
1997 | Poliovirus infection and expression of the poliovirus protein 2B provoke the dis... | |
1997 | Membrane permeability changes induced in Escherichia coli by the SH protein of h... | |
1997 | Cleavage of p220 by purified poliovirus 2A(pro) in cell-free systems: Effects on... | |
1997 | Poliovirus protein 2BC increases cytosolic free calcium concentrations | |
1997 | The yeast Saccharomyces cerevisiae as a genetic system for obtaining variants of... | |
1997 | Antiviral activity of medicinal plant extracts | |
1997 | Entry of semliki forest virus into cells: Effects of concanamycin A andnigericin... | |
1997 | Erratum: Permeabilization of mammalian cells to proteins: Poliovirus 2A(pro) as ... | |
1997 | Permeabilization of mammalian cells to proteins: Poliovirus 2A(pro) as a probe t... | |
1997 | The N-terminal Arg-rich region of human immunodeficiency virus types 1 and 2 and... | |
1996 | Hybrid proteins between pseudomonas aeruginosa exotoxin A and poliovirus 2Apro c... | |
1996 | Membrane permeabilization by poliovirus proteins 2B and 2BC | |
1996 | Screening for membrane-permeabilizing mutants of the poliovirus protein3AB | |
1996 | The entry of reovirus into L cells is dependent on vacuolarproton-ATPase activit... | |
1996 | Human immunodeficiency virus (HIV) Nef is an RNA binding protein in cell-free sy... | |
1995 | A poliovirus 2A(pro) mutant unable to cleave 3CD shows inefficient viral protein... | |
1995 | A human virus protein, poliovirus protein 2BC, induces membrane proliferation an... | |
1995 | Effects of Poliovirus 2Apro on Vaccinia Virus Gene Expression | |
1995 | Expression of poliovirus 2Apro in mammalian cells: effects on translation | |
1995 | Poliovirus 2A(pro) expression inhibits growth of yeast-cells | |
1995 | Mutations in the hydrophobic domain of poliovirus protein 3ab abrogateits permea... | |
1995 | Poliovirus protein 2c contains 2 regions involved in RNA-binding activity | |
1995 | Cloning and inducible synthesis of poliovirus nonstructural proteins in saccharo... | |
1995 | Requirement for vacuolar proton-atpase activity during entry of influenza-virus ... | |
1995 | Induction of membrane proliferation by poliovirus proteins 2c and 2bc | |
1995 | Modification of membrane-permeability by animal viruses | |
1995 | Enhanced intracellular calcium concentration during poliovirus infection | |
1995 | Membrane permeabilization by different regions of the human immunodeficiency vir... | |
1995 | Efficient Cleavage of p220 by Poliovirus 2Apro Expression in Mammalian Cells: Ef... | |
1995 | Monensin and nigericin prevent the inhibition of host translation by poliovirus,... | |
1994 | Action of brefeldin-a on translation in semliki forest virus-infected hela-cells... | |
1994 | Entry of animal viruses and macromolecules into cells | |
1994 | Concanamycin-a blocks influenza-virus entry into cells under acidi cconditions | |
1994 | Concanamycin-a - a powerful inhibitor of enveloped animal-virus entry into cells | |
1994 | Influenza-virus M2 protein modifies membrane-permeability in escherichia-coli-ce... | |
1994 | Picornavirus inhibitors | |
1994 | Hybrid proteins between Pseudomonas exotoxin A and poliovirus protease 2Apro | |
1994 | Involvement of the vacuolar H+-ATPase in animal virus entry | |
1994 | Orobol: An inhibitor of vesicular stomatitis virus that blocks the synthesis of ... | |
1993 | High level expression in Escherichia coli cells and purification of poliovirus p... | |
1993 | Brefeldin A blocks protein glycosylation and RNA replication of vesicular stomat... | |
1993 | Entry of poliovirus into cells does not require a low-ph step | |
1993 | Activation of phospholipase-activity during semliki forest virus-infection | |
1993 | Enhancement of phospholipase activity during poliovirus infection | |
1992 | Inducible expression of a toxic poliovirus membrane-protein inescherichia-coli -... | |
1992 | Involvement of membrane traffic in the replication of poliovirus genomes effects... | |
1992 | Cloning and inducible synthesis of poliovirus nonstructural proteins | |
1992 | Lack of direct correlation between p220 cleavage and the shutoff of host transla... | |
1992 | Significant anti-hiv activity of new modified polyanionic polymers in vitro | |
1992 | Gliotoxin: Inhibitor of poliovirus RNA synthesis that blocks the viral RNA polym... | |
1991 | Inhibitors of poliovirus uncoating efficiently block the early membrane permeabi... | |
1991 | Cell type determines the relative proportions of (-) and (+) strand RNA during p... | |
1991 | Effects of fatty-acids on lipid-synthesis and viral-RNA replication in polioviru... | |
1991 | Synthesis of semliki forest virus-RNA requires continuous lipid-synthesis | |
1991 | Cerulenin, an inhibitor of lipid-synthesis, blocks vesicular stomatitis-virus RN... | |
1991 | Mechanism of inhibition of hsv-1 replication by tumor-necrosis-factor and interf... | |
1990 | 6-(3,4-Dichlorophenoxy)-3-(ethylthio)-2-pyridincarbonitrile inhibits poliovirus ... | |
1990 | Phospholipid biosynthesis and poliovirus genome replication, 2 coupled phenomena | |
1989 | Restriction of poliovirus RNA translation in a human monocytic cell line | |
1989 | Post-translational modifications of poliovirus proteins | |
1989 | Modification of membrane-permeability by animal viruses | |
1989 | Degradation of cellular proteins during poliovirus infection: Studies by two-dim... | |
1989 | Human gamma interferon and tumor necrosis factor exert a synergistic blockade on... | |
1988 | MEGALOMYCIN-C, A MACROLIDE ANTIBIOTIC THAT BLOCKS PROTEIN GLYCOSYLATION AND SHOW... | |
1988 | Mode of action of a new type of UDP-glucose analog against herpesvirus replicati... | |
1988 | Exogenous phospholipase-c permeabilizes mammalian-cells to proteins | |
1988 | Effect of heterocyclic-analogs of triphenylmethane dyes against trypanosoma-cruz... | |
1988 | Reovirus type-3 synthesizes proteins in interferon-treated hela-cells without re... | |
1988 | The heat-shock response in trypanosoma-cruzi | |
1988 | Inhibition of natural-killer cyto-toxicity by extracellularppp(a2'p5')na oligonu... | |
1988 | The P2 and P3 regions of the poliovirus genome are preferentially translated at ... | |
1987 | Polysaccharides as antiviral agents: antiviral activity of carrageenan | |
1987 | ANIMAL VIRUSES PROMOTE THE ENTRY OF POLYSACCHARIDES WITH ANTIVIRAL ACTIVITY INTO... | |
1987 | Proteins are cointernalized with virion particles during early infection | |
1987 | Proteins synthesized in african swine fever virus-infected cells analyzed by two... | |
1987 | Baciphelacin - a new eukaryotic translation inhibitor | |
1987 | Adenovirus infection reverses the antiviral state induced by human interferon | |
1987 | Control of membrane-permeability in animal-cells by divalent-cations | |
1987 | Effects of extracellular cations on translation in poliovirus-infected cells | |
1987 | Cation content in poliovirus-infected HeLa cells | |
1987 | Action of 3-methylquercetin on poliovirus RNA replication | |
1987 | Hexose-modified antiviral analogs of uridine 5'-diphosphate glucose derivatives | |
1987 | Ribavirin cures cells of a persistent infection with foot-and-mouth disease viru... | |
1986 | NEW AGENTS ACTIVE AGAINST AFRICAN SWINE FEVER VIRUS | |
1986 | Specific proteins synthesized during the viral lytic cycle in vaccinia virus-inf... | |
1986 | The inhibition of nucleic acid synthesis in encephalomyocarditis virus-infected ... | |
1986 | Antirhinovirus compound 44 081 R.P. inhibits virus uncoating | |
1986 | 3-methylquercetin is a potent and selective inhibitor of poliovirusrna-synthesis | |
1986 | External atp permeabilizes transformed-cells to macromolecules | |
1985 | Uridine 5'-diphosphate glucose analogs - inhibitors of protein glycosylation tha... | |
1985 | Synthesis and antiviral evaluation of nucleosides of 5-methylimidazole-4-carboxa... | |
1985 | Analogs of uridinediphosphatehexoses - a new type of protein glycosylation inhib... | |
1985 | Modification of membrane-permeability during semliki forest virus-infection | |
1985 | The regulation of translation in reovirus-infected cells | |
1985 | Increased inhibition of cellular RNA synthesis by alpha-amanitin during entry of... | |
1985 | Mildiomycin: A nucleoside antibiotic that inhibits protein synthesis | |
1984 | Screening for new compounds with antiherpes activity | |
1984 | Comparison of the antiviral action of different human interferons against DNA an... | |
1984 | Action of human-lymphoblastoid interferon on hela-cells infected with RNA-contai... | |
1984 | Molecular-bases for the action and selectivity of nucleoside antibiotics | |
1984 | ANTIHERPESVIRUS ACTION OF ATROPINE | |
1984 | pppA2'p5A' blocks vesicular stomatitis virus replication in intact cells | |
1984 | Action of oligomycin on cultured mammalian cells. Permeabilization to translatio... | |
1984 | Formation of non-infective herpesvirus particles in cultured cells treated with ... | |
1984 | Synthesis of heat-shock proteins in HeLa cells: Inhibition by virus infection | |
1983 | Effect of interferon treatment on blockade of protein-synthesis induced by polio... | |
1983 | Cellular RNA is not degraded in interferon-treated hela-cells after poliovirus i... | |
1983 | Permeabilization of cells during animal virus-infection | |
1983 | Antiviral effects of hygromycin B, a translation inhibitor nonpermeant to uninfe... | |
1983 | Modification of membrane permeability in poliovirus-infected HeLa cells: Effect ... | |
1983 | Do cells treated with human interferon survive virus infection? | |
1982 | Relationship between membrane integrity and the inhibition of host translation i... | |
1982 | Protein-synthesis in hela-cells double-infected with encephalomyocarditis virus ... | |
1982 | Translation of capped virus messenger-RNA in encephalomyocarditis virus-infected... | |
1982 | Modification of membrane-permeability in vaccinia virus-infected cells | |
1982 | Molecular Basis of the Permeabilization of Mammalian Cells by Ionophores | |
1982 | Translation of capped viral mRNAs in poliovirus-infected HeLa cells. | |
1981 | Thionins - plant peptides that modify membrane-permeability in cultured mammalia... | |
1981 | Action of nucleotide derivatives on translation in encephalomyocarditis virus-in... | |
1981 | Modification of membrane-permeability induced by animal viruses early in infecti... | |
1981 | Selective inhibition of cellular protein synthesis by amphotericin B in EMC viru... | |
1981 | Permeabilization of mammalian cells to proteins by the ionophore nigericin | |
1981 | Reversion by hypotonic medium of the shutoff of protein synthesis induced by enc... | |
1981 | Relationship between Membrane Permeability and the Translation Capacity of Human... | |
1981 | Protein synthesis and membrane integrity in interferon-treated HeLa cells infect... | |
1981 | Reversal by hypotonic medium of the antiviral state induced by lymphoblastoid in... | |
1980 | Viral-infection permeabilized mammalian-cells to protein toxins | |
1980 | Selective-inhibition of translation in transformed-cells | |
1980 | Antibiotics that specifically block translation in virus-infected cells | |
1980 | Molecular-biology of animal virus-infection | |
1980 | Inhibition of animal virus production by means of translation inhibitors unable ... | |
1980 | Action of Membrane‐Active Compounds on Mammalian Cells: Permeabilization of Huma... | |
1979 | Selective inhibition of protein synthesis in virus-infected mammalian cells. | |
1979 | Regulation of translation of eukaryotic virus mRNAs. | |
1979 | Compounds affecting membranes that inhibit protein synthesis in yeast | |
1978 | Membrane leakiness after viral-infection and a new approach to development of an... | |
1978 | Inhibition, by selected antibiotics, of protein synthesis in cells growing in ti... | |
1977 | Enzymic and nonenzymic translocation by yeast polysomes - site of action of a nu... | |
1977 | Inhibition of cell functions after viral-infection - proposed general mechanism | |
1977 | Do viruses use calcium-ions to shut off host-cell functions - reply | |
1977 | Do viruses use calcium ions to shut off host cell functions? | |
1976 | Initiation of polypeptide-chain by reticulocyte cell-free systems -survey of dif... | |
1976 | Antibiotics and compounds affecting translation by eukaryotic ribosomes specific... | |
1976 | Binding of aminoacyl-transfer-RNA to rat-liver ribosomal-proteins | |
1976 | Sodium ions and shut-off of host-cell protein-synthesis by pico RNA viruses | |
1976 | Site of Action of Ricin on the Ribosome | |
1976 | Specific Inhibition of Translocation by Tubulosine in Eukaryotic Polysomes | |
1975 | Ribosome inactivation by toxic lectins abrin and ricin - kinetics of enzymic act... | |
1975 | Effects of ricin on ribosomal sites involved in interaction of elongation-factor... | |
1975 | Involvement of sulfhydryl groups in peptidyl transferase center of eukaryotic ri... | |
1975 | Narciclasine - antitumor alkaloid which blocks peptide-bond formation by eukaryo... | |
1974 | Enhancement of polypeptide-synthesis in mammalian systems by methylxanthines | |
1974 | [29] The Elongation Steps in Protein Synthesis by Eukaryotic Ribosomes: Effects ... | |
1973 | Differences in eukaryotic ribosomes detected by selective action of an antibioti... | |
1973 | Trichodermin group of antibiotics, inhibitors of peptide-bond formation by eukar... | |
1973 | Ribosomal sites involved in binding of aminoacyl transfer RNA and ef 2 -mode of ... | |
1972 | Survey of inhibitors in different steps of protein synthesis by mammalian riboso... |
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