Timeline
enero de 1974
Doctorado: Doctor/a
Reconocimientos Investigación
Sexenios
6
Año último Sexenio: 2007
Timeline
marzo de 1986
Catedrático de universidad. Biología Molecular
Universidad Autónoma de Madrid
1986 - 2019
enero de 1985
Profesor Titular Universidad. Biología Molecular
Universidad Autónoma de Madrid
1985 - 1986
julio de 1975
Colaborador Científico. Biología Molecular
Universidad Autónoma de Madrid
1975 - 1978
Reconocimientos Docentes
Quinquenios
6
Año último Quinquenio: 2001
Publicaciones en Altmetrics
| 2019 | Brain Microbiota in Huntington’s Disease Patients | |
| 2019 | Searching for Bacteria in Neural Tissue From Amyotrophic Lateral Sclerosis | |
| 2019 | System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus I... | |
| 2018 | Human and Microbial Proteins From Corpora Amylacea of Alzheimer's Disease | |
| 2018 | Mechanisms of virus-induced cell toxicity: A general overview | |
| 2018 | The Regulation of Translation in Alphavirus-Infected Cells. | |
| 2018 | Multiple sclerosis and mixed microbial infections. Direct identification of fung... | |
| 2018 | Infection of Fungi and Bacteria in Brain Tissue From Elderly Persons and Patient... | |
| 2018 | The Initiation Factors eIF2, eIF2A, eIF2D, eIF4A, and eIF4G Are Not Involved in ... | |
| 2017 | Alzheimer's Disease and Fungal Infection | |
| 2017 | Identification of Fungal Species in Brain Tissue from Alzheimer's Disease by Nex... | |
| 2017 | Fungal infection in neural tissue of patients with amyotrophic lateral sclerosis... | |
| 2017 | Polymicrobial Infections In Brain Tissue From Alzheimer's Disease Patients. | |
| 2017 | Translation of Sindbis Subgenomic mRNA is Independent of eIF2, eIF2A and eIF2D | |
| 2016 | Corpora Amylacea of Brain Tissue from Neurodegenerative Diseases Are Stained wit... | |
| 2016 | Fungal Enolase, beta-Tubulin, and Chitin Are Detected in Brain Tissue from Alzhe... | |
| 2016 | A Viral mRNA Motif at the 3′-Untranslated Region that Confers Translatability in... | |
| 2015 | Influence of glutathione availability on cell damage induced by human immunodefi... | |
| 2015 | Impact of Vesicular Stomatitis Virus M Proteins on Different Cellular Functions | |
| 2015 | Different Brain Regions are Infected with Fungi in Alzheimer's Disease | |
| 2015 | Evidence for fungal infection in cerebrospinal fluid and brain tissue from patie... | |
| 2015 | Direct visualization of fungal infection in brains from patients with Alzheimer'... | |
| 2015 | Differential action of pateamine A on translation of genomic and subgenomic mRNA... | |
| 2015 | Cerebrospinal Fluid from Alzheimer's Disease Patients Contains Fungal Proteins a... | |
| 2015 | Viroporins: Structures and functions beyond cell membrane permeabilization | |
| 2014 | L protease from foot and mouth disease virus confers eIF2-independent translatio... | |
| 2014 | Initiation codon selection is accomplished by a scanning mechanism without cruci... | |
| 2014 | Inhibition of host protein synthesis by Sindbis virus: correlation with viral RN... | |
| 2014 | Aplidin: first in class compound targeting EEF1A in tumor cells | |
| 2014 | Alzheimer's disease and disseminated mycoses | |
| 2014 | Fungal infection in patients with Alzheimer's disease | |
| 2014 | Corrigendum: Participation of eIF4F complex in Junin virus infection: Blockage o... | |
| 2013 | Poliovirus 2A Protease Triggers a Selective Nucleo-Cytoplasmic Redistribution of... | |
| 2013 | Requirements for eIF4A and eIF2 during translation of Sindbis virus subgenomic m... | |
| 2013 | Participation Of Eif4F Complex In Junin Virus Infection: Blockage Of Eif4E Does ... | |
| 2013 | Fungal infection in cerebrospinal fluid from some patients with multiple scleros... | |
| 2013 | Translation of viral mRNAs that do not require eIF4E is blocked by the inhibitor... | |
| 2013 | Phosphorylation of eIF2 alpha is responsible for the failure of the picornavirus... | |
| 2012 | Translation Directed by Hepatitis A Virus IRES in the Absence of Active eIF4F Co... | |
| 2012 | Membrane-active peptides derived from picornavirus 2B viroporin | |
| 2012 | Viroporins: Structure and biological functions | |
| 2012 | A non-infectious cell-based phenotypic assay for the assessment of HIV-1suscepti... | |
| 2011 | Fungal infection in a patient with multiple sclerosis | |
| 2011 | Membrane Integration of Poliovirus 2B Viroporin | |
| 2011 | Alternative splicing, a new target to block cellular gene expression bypolioviru... | |
| 2011 | Translation without eIF2 Promoted by Poliovirus 2A Protease | |
| 2011 | Translation of Viral mRNA without Active eIF2: The Case ofPicornaviruses | |
| 2011 | Functional impairment of eIF4A and elF4G factors correlates withinhibition of in... | |
| 2011 | The Multifaceted Poliovirus 2A Protease: Regulation of Gene Expressionby Picorna... | |
| 2010 | Translation Driven by Picornavirus IRES Is Hampered from Sindbis VirusReplicons:... | |
| 2010 | Cell permeabilization by poliovirus 2B viroporin triggers bystanderpermeabilizat... | |
| 2010 | Association between multiple sclerosis and Candida species: evidencefrom a case-... | |
| 2009 | RNA nuclear export is blocked by poliovirus 2A protease and isconcomitant with n... | |
| 2009 | Regulation of Host Translational Machinery by African Swine Fever Virus | |
| 2009 | Dual Mechanism for the Translation of Subgenomic mRNA from Sindbis Virusin Infec... | |
| 2009 | A peptide based on the pore-forming domain of pro-apoptotic poliovirus2B viropor... | |
| 2009 | Translation of mRNAs from Vesicular Stomatitis Virus and Vaccinia VirusIs Differ... | |
| 2009 | HIV-1 Protease Inhibits Cap- and Poly(A)-Dependent Translation uponeIF4GI and PA... | |
| 2008 | Functional and structural characterization of 2B viroporin membranolyticdomains | |
| 2007 | Viroporins from RNA viruses induce caspase-dependent apoptosis | |
| 2007 | Plasma membrane-porating domain in poliovirus 2B protein. A shortpeptide mimics ... | |
| 2007 | Fungal infection in patients with serpiginous choroiditis or acute zonaloccult o... | |
| 2007 | Differential inhibition of cellular and Sindbis virus translation bybrefeldin A | |
| 2007 | Viral translation is coupled to transcription in sindbis virus-infectedcells | |
| 2007 | Evolution of antibody response and fungal antigens in the serum of apatient infe... | |
| 2007 | Attachment and entry of Candida famata in monocytes and epithelial cells | |
| 2006 | Differential cleavage of eIF4GI and eIF4GII in mammalian cells - Effectson trans... | |
| 2006 | HIV protease cleaves poly(A)-binding protein | |
| 2006 | Antiviral effect of the mammalian translation initiation factor 2 alphakinase GC... | |
| 2006 | Translational resistance of late alphavirus mRNA to eIF2 alphaphosphorylation: a... | |
| 2005 | Viroporin activity of murine hepatitis virus E protein | |
| 2005 | Regulation of HIV-1 env mRNA translation by Rev protein | |
| 2005 | Translation of Sindbis virus 26 S mRNA does not require intacteukariotic initiat... | |
| 2005 | Involvement of HIV-1 protease in virus-induced cell killing | |
| 2005 | Requirement of the vesicular system for membrane permeabilization bySindbis viru... | |
| 2005 | Isolation of Candida famata from a patient with acute zonal occult outer retinop... | |
| 2004 | Membrane-permeabilizing motif in Semliki forest virus E1 glycoprotein | |
| 2004 | Individual expression of poliovirus 2A(pro) and 3C(pro) inducesactivation of cas... | |
| 2003 | Cell killing by HIV-1 protease | |
| 2003 | Cleavage of eIF4G by HIV-1 protease: effects on translation | |
| 2003 | Viroporins | |
| 2003 | The eukaryotic translation initiation factor 4GI is cleaved by differentretrovir... | |
| 2003 | Mechanisms of membrane permeabilization by picornavirus 2B viroporin | |
| 2003 | Individual expression of Sindbis virus glycoproteins. E1 alone promotescell fusi... | |
| 2002 | Interfacial domains in Sindbis virus 6K protein - Detection andfunctional charac... | |
| 2002 | Viroporin-mediated membrane permeabilization - Pore formation bynonstructural po... | |
| 2002 | Antipoliovirus flavonoids from Psiadia dentata | |
| 2002 | Antiviral activity of seven iridoids, three saikosaponins and one phenylpropanoi... | |
| 2001 | HIV-1 protease cleaves eukaryotic initiation factor 4G and inhibitscap-dependent... | |
| 2001 | Sindbis virus variant with a deletion in the 6K gene shows defects inglycoprotei... | |
| 2001 | Entry of poliovirus into cells is blocked by valinomycin andconcanamycin A | |
| 2001 | Human immunodeficiency virus type 1 VPU protein affects Sindbis virus glycoprote... | |
| 2000 | Search for antiviral activity in higher plant extracts | |
| 2000 | Eukaryotic translation initiation factor 4GI is a cellular target forNS1 protein... | |
| 2000 | Poliovirus induces apoptosis in the human U937 promonocytic cell line | |
| 2000 | A stable HeLa cell line that inducibly expresses poliovirus 2A(pro):Effects on c... | |
| 2000 | The amino-terminal nine amino acid sequence of poliovirus capsid VP4protein is s... | |
| 2000 | Poliovirus protease 3C(pro) kills cells by apoptosis | |
| 1999 | Antiviral activity of some South American medicinal plants | |
| 1999 | Antiviral activity of Bolivian plant extracts | |
| 1999 | Cleavage of eukaryotic translation initiation factor 4G by exogenously added hyb... | |
| 1998 | Mutational analysis of poliovirus 2A(pro) - Distinct inhibitoryfunctions of 2A(p... | |
| 1998 | Poliovirus 2A proteinase cleaves directly the eIF-4G subunit of eIF-4Fcomplex | |
| 1998 | The human immunodeficiency virus type 1 Vpu protein enhances membrane permeabili... | |
| 1998 | Co-expression of human elF-4G and poliovirus 2A(pro) in Saccharomyces cerevisiae... | |
| 1998 | Genetic analysis of poliovirus protein 3A: Characterization of a non-cytopathic ... | |
| 1997 | Membrane permeability changes induced in Escherichia coli by the SH protein of h... | |
| 1997 | Cleavage of p220 by purified poliovirus 2A(pro) in cell-free systems:Effects on ... | |
| 1997 | The yeast Saccharomyces cerevisiae as a genetic system for obtainingvariants of ... | |
| 1997 | Antiviral activity of medicinal plant extracts | |
| 1997 | Permeabilization of mammalian cells to proteins: Poliovirus 2A(pro) as aprobe to... | |
| 1997 | Entry of semliki forest virus into cells: Effects of concanamycin A andnigericin... | |
| 1997 | Erratum: Permeabilization of mammalian cells to proteins: Poliovirus 2A(pro) as ... | |
| 1997 | The N-terminal Arg-rich region of human immunodeficiency virus types 1 and 2 and... | |
| 1996 | Membrane permeabilization by poliovirus proteins 2B and 2BC | |
| 1996 | Screening for membrane-permeabilizing mutants of the poliovirus protein3AB | |
| 1996 | Human immunodeficiency virus (HIV) Nef is an RNA binding protein in cell-free sy... | |
| 1995 | A human virus protein, poliovirus protein 2BC, induces membrane proliferation an... | |
| 1995 | Effects of Poliovirus 2Apro on Vaccinia Virus Gene Expression | |
| 1995 | Expression of poliovirus 2A(pro) in mammalian cells: Effects ontranslation | |
| 1995 | Efficient cleavage of p220 by poliovirus 2a(pro) expression in mammalian-cells -... | |
| 1995 | Poliovirus 2A(pro) expression inhibits growth of yeast-cells | |
| 1995 | Mutations in the hydrophobic domain of poliovirus protein 3ab abrogateits permea... | |
| 1995 | Cloning and inducible synthesis of poliovirus nonstructural proteins in saccharo... | |
| 1995 | Induction of membrane proliferation by poliovirus proteins 2c and 2bc | |
| 1995 | Modification of membrane-permeability by animal viruses | |
| 1995 | Poliovirus protein 2C contains two regions involved in RNA binding activity | |
| 1994 | Hybrid proteins between pseudomonas exotoxin-a and poliovirusprotease-2a(pro) | |
| 1994 | Involvement of the vacuolar h+-atpase in animal virus entry | |
| 1994 | Action of brefeldin-a on translation in semliki forest virus-infected hela-cells... | |
| 1994 | Entry of animal viruses and macromolecules into cells | |
| 1994 | Concanamycin-a blocks influenza-virus entry into cells under acidi cconditions | |
| 1994 | Concanamycin-a - a powerful inhibitor of enveloped animal-virus entry into cells | |
| 1994 | Influenza-virus M2 protein modifies membrane-permeability in escherichia-coli-ce... | |
| 1994 | Orobol - an inhibitor of vesicular stomatitis-virus that blocks the synthesis of... | |
| 1994 | Picornavirus inhibitors | |
| 1993 | Brefeldin A blocks protein glycosylation and RNA replication of vesicular stomat... | |
| 1993 | High level expression in escherichia coli cells and purification of poliovirus p... | |
| 1993 | Enhancement of phospholipase-activity during poliovirus infection | |
| 1993 | Activation of phospholipase-activity during semliki forest virus-infection | |
| 1992 | Inducible expression of a toxic poliovirus membrane-protein inescherichia-coli -... | |
| 1992 | Involvement of membrane traffic in the replication of poliovirus genomes effects... | |
| 1992 | Cloning and inducible synthesis of poliovirus nonstructural proteins | |
| 1992 | Lack of direct correlation between p220 cleavage and the shutoff of host transla... | |
| 1992 | Significant anti-hiv activity of new modified polyanionic polymers in vitro | |
| 1991 | Effects of fatty-acids on lipid-synthesis and viral-RNA replication in polioviru... | |
| 1991 | Synthesis of semliki forest virus-RNA requires continuous lipid-synthesis | |
| 1991 | Cell type determines the relative proportions of (-) and (+) strand RNA during p... | |
| 1991 | Cerulenin, an inhibitor of lipid-synthesis, blocks vesicular stomatitis-virus RN... | |
| 1991 | Mechanism of inhibition of hsv-1 replication by tumor-necrosis-factor and interf... | |
| 1990 | 6-(3,4-Dichlorophenoxy)-3-(ethylthio)-2-pyridincarbonitrile inhibits poliovirus ... | |
| 1990 | Phospholipid biosynthesis and poliovirus genome replication, 2 coupled phenomena | |
| 1989 | Restriction of poliovirus RNA translation in a human monocytic cell-line | |
| 1989 | Post-translational modifications of poliovirus proteins | |
| 1989 | Modification of membrane-permeability by animal viruses | |
| 1988 | MEGALOMYCIN-C, A MACROLIDE ANTIBIOTIC THAT BLOCKS PROTEIN GLYCOSYLATION AND SHOW... | |
| 1988 | Mode of action of a new type of UDP-glucose analog against herpesvirus replicati... | |
| 1988 | Exogenous phospholipase-c permeabilizes mammalian-cells to proteins | |
| 1988 | Effect of heterocyclic-analogs of triphenylmethane dyes against trypanosoma-cruz... | |
| 1988 | Reovirus type-3 synthesizes proteins in interferon-treated hela-cells without re... | |
| 1988 | The heat-shock response in trypanosoma-cruzi | |
| 1988 | Inhibition of natural-killer cyto-toxicity by extracellularppp(a2'p5')na oligonu... | |
| 1988 | The P2 and P3 regions of the poliovirus genome are preferentially translated at ... | |
| 1987 | Polysaccharides as antiviral agents: antiviral activity of carrageenan | |
| 1987 | ANIMAL VIRUSES PROMOTE THE ENTRY OF POLYSACCHARIDES WITH ANTIVIRAL ACTIVITY INTO... | |
| 1987 | Proteins are cointernalized with virion particles during early infection | |
| 1987 | Proteins synthesized in african swine fever virus-infected cells analyzed by two... | |
| 1987 | Baciphelacin - a new eukaryotic translation inhibitor | |
| 1987 | Adenovirus infection reverses the antiviral state induced by human interferon | |
| 1987 | Control of membrane-permeability in animal-cells by divalent-cations | |
| 1987 | Effects of extracellular cations on translation in poliovirus-infected cells | |
| 1987 | Cation content in poliovirus-infected HeLa cells | |
| 1987 | Hexose-modified antiviral analogs of uridine 5'-diphosphate glucose derivatives | |
| 1986 | NEW AGENTS ACTIVE AGAINST AFRICAN SWINE FEVER VIRUS | |
| 1986 | The inhibition of nucleic acid synthesis in encephalomyocarditis virus-infected ... | |
| 1986 | Antirhinovirus compound 44 081 R.P. inhibits virus uncoating | |
| 1986 | 3-methylquercetin is a potent and selective inhibitor of poliovirusrna-synthesis | |
| 1986 | External atp permeabilizes transformed-cells to macromolecules | |
| 1985 | Uridine 5'-diphosphate glucose analogs - inhibitors of protein glycosylation tha... | |
| 1985 | Synthesis and antiviral evaluation of nucleosides of 5-methylimidazole-4-carboxa... | |
| 1985 | Analogs of uridinediphosphatehexoses - a new type of protein glycosylation inhib... | |
| 1985 | Modification of membrane-permeability during semliki forest virus-infection | |
| 1985 | Increased inhibition of cellular RNA synthesis by alpha-amanitin during entry of... | |
| 1985 | Mildiomycin: A nucleoside antibiotic that inhibits protein synthesis | |
| 1985 | Increased inhibition of cellular RNA-synthesis by alpha-amanitin during entry of... | |
| 1985 | The regulation of translation in reovirus-infected cells | |
| 1984 | Screening for new compounds with antiherpes activity | |
| 1984 | Comparison of the antiviral action of different human interferons against DNA an... | |
| 1984 | Action of human-lymphoblastoid interferon on hela-cells infected with RNA-contai... | |
| 1984 | Formation of non-infective herpes virus particles in cultured-cells treated with... | |
| 1984 | Molecular-bases for the action and selectivity of nucleoside antibiotics | |
| 1984 | Synthesis of heat-shock proteins in hela-cells - inhibition by virus-infection | |
| 1984 | ANTIHERPESVIRUS ACTION OF ATROPINE | |
| 1984 | Action of oligomycin on cultured mammalian cells. Permeabilization to translatio... | |
| 1983 | Effect of interferon treatment on blockade of protein-synthesis induced by polio... | |
| 1983 | Cellular RNA is not degraded in interferon-treated hela-cells after poliovirus i... | |
| 1983 | Modification of membrane-permeability in poliovirus-infected hela-cells effect o... | |
| 1983 | Permeabilization of cells during animal virus-infection | |
| 1983 | Antiviral effects of hygromycin B, a translation inhibitor nonpermeant to uninfe... | |
| 1983 | Do cells treated with human interferon survive virus infection? | |
| 1982 | Relationship between membrane integrity and the inhibition of host translation i... | |
| 1982 | Protein-synthesis in hela-cells double-infected with encephalomyocarditis virus ... | |
| 1982 | Translation of capped virus messenger-RNA in encephalomyocarditis virus-infected... | |
| 1982 | Modification of membrane-permeability in vaccinia virus-infected cells | |
| 1982 | Molecular Basis of the Permeabilization of Mammalian Cells by Ionophores | |
| 1982 | Translation of capped viral mRNAs in poliovirus-infected HeLa cells. | |
| 1981 | Thionins - plant peptides that modify membrane-permeability in cultured mammalia... | |
| 1981 | Permeabilization of mammalian-cells to proteins by the ionophorenigericin | |
| 1981 | Protein-synthesis and membrane integrity in interferon-treated hela-cells infect... | |
| 1981 | Action of nucleotide derivatives on translation in encephalomyocarditis virus-in... | |
| 1981 | Selective-inhibition of cellular protein-synthesis by amphotericin-b inemc virus... | |
| 1981 | Modification of membrane-permeability induced by animal viruses early in infecti... | |
| 1981 | Relationship between Membrane Permeability and the Translation Capacity of Human... | |
| 1981 | Reversal by hypotonic medium of the antiviral state induced by lymphoblastoid in... | |
| 1980 | Viral-infection permeabilized mammalian-cells to protein toxins | |
| 1980 | Action of membrane-active compounds on mammalian-cells -permeabilization of huma... | |
| 1980 | Selective-inhibition of translation in transformed-cells | |
| 1980 | Antibiotics that specifically block translation in virus-infected cells | |
| 1980 | Molecular-biology of animal virus-infection | |
| 1980 | Inhibition of animal virus production by means of translation inhibitors unable ... | |
| 1979 | Compounds affecting membranes that inhibit protein synthesis in yeast | |
| 1978 | Membrane leakiness after viral-infection and a new approach to development of an... | |
| 1978 | Inhibition, by selected antibiotics, of protein synthesis in cells growing in ti... | |
| 1977 | Enzymic and nonenzymic translocation by yeast polysomes - site of action of a nu... | |
| 1977 | Inhibition of cell functions after viral-infection - proposed general mechanism | |
| 1977 | Do viruses use calcium-ions to shut off host-cell functions - reply | |
| 1977 | Do viruses use calcium ions to shut off host cell functions? | |
| 1976 | Initiation of polypeptide-chain by reticulocyte cell-free systems -survey of dif... | |
| 1976 | Antibiotics and compounds affecting translation by eukaryotic ribosomes specific... | |
| 1976 | Binding of aminoacyl-transfer-RNA to rat-liver ribosomal-proteins | |
| 1976 | Sodium ions and shut-off of host-cell protein-synthesis by pico RNA viruses | |
| 1976 | Site of Action of Ricin on the Ribosome | |
| 1976 | Specific Inhibition of Translocation by Tubulosine in Eukaryotic Polysomes | |
| 1975 | Ribosome inactivation by toxic lectins abrin and ricin - kinetics of enzymic act... | |
| 1975 | Effects of ricin on ribosomal sites involved in interaction of elongation-factor... | |
| 1975 | Involvement of sulfhydryl groups in peptidyl transferase center of eukaryotic ri... | |
| 1975 | Narciclasine - antitumor alkaloid which blocks peptide-bond formation by eukaryo... | |
| 1974 | Enhancement of polypeptide-synthesis in mammalian systems by methylxanthines | |
| 1974 | [29] The Elongation Steps in Protein Synthesis by Eukaryotic Ribosomes: Effects ... | |
| 1973 | Differences in eukaryotic ribosomes detected by selective action of an antibioti... | |
| 1973 | Trichodermin group of antibiotics, inhibitors of peptide-bond formation by eukar... | |
| 1973 | Ribosomal sites involved in binding of aminoacyl transfer RNA and ef 2 -mode of ... | |
| 1972 | Survey of inhibitors in different steps of protein synthesis by mammalian riboso... |
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