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Analysis of institutional authors

Barahona Martin, EmmaAuthorMartínez-Granero FAuthorAna NavazoAuthorRedondo Nieto, MiguelAuthorRivilla Palma, RafaelAuthorMartin Basanta, MartaCorresponding Author

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October 19, 2020
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The Gac-Rsm and SadB signal transduction pathways converge on Algu to downregulate motility in Pseudomonas fluorescens

Publicated to:PLoS ONE. 7 (2): e31765-e31765 - 2012-02-20 7(2), DOI: 10.1371/journal.pone.0031765

Authors: Martinez-Granero, Francisco; Navazo, Ana; Barahona, Emma; Redondo-Nieto, Miguel; Rivilla, Rafael; Martin, Marta

Affiliations

Univ Autonoma Madrid, Dept Biol, Madrid, Spain - Author
Universidad Autónoma de Madrid - Author

Abstract

Flagella mediated motility in Pseudomonas fluorescens F113 is tightly regulated. We have previously shown that motility is repressed by the GacA/GacS system and by SadB through downregulation of the fleQ gene, encoding the master regulator of the synthesis of flagellar components, including the flagellin FliC. Here we show that both regulatory pathways converge in the regulation of transcription and possibly translation of the algU gene, which encodes a sigma factor. AlgU is required for multiple functions, including the expression of the amrZ gene which encodes a transcriptional repressor of fleQ. Gac regulation of algU occurs during exponential growth and is exerted through the RNA binding proteins RsmA and RsmE but not RsmI. RNA immunoprecipitation assays have shown that the RsmA protein binds to a polycistronic mRNA encoding algU, mucA, mucB and mucD, resulting in lower levels of algU. We propose a model for repression of the synthesis of the flagellar apparatus linking extracellular and intracellular signalling with the levels of AlgU and a new physiological role for the Gac system in the downregulation of flagella biosynthesis during exponential growth. © 2012 Martínez-Granero et al.

Keywords

Administração pública e de empresas, ciências contábeis e turismoAdministração, ciências contábeis e turismoAgricultural and biological sciences (miscellaneous)AnthropologyAntropologia / arqueologiaArchaeologyArquitetura, urbanismo e designAstronomia / físicaBiochemistry, genetics and molecular biology (miscellaneous)BiodiversidadeBiologyBiotecnologíaCiência da computaçãoCiência de alimentosCiência política e relações internacionaisCiências agrárias iCiências ambientaisCiências biológicas iCiências biológicas iiCiências biológicas iiiCiências sociais aplicadas iComunicação e informaçãoDemographyDireitoEconomiaEducaçãoEducação físicaEnfermagemEngenharias iEngenharias iiEngenharias iiiEngenharias ivEnsinoEnvironmental studiesFarmaciaGeneral agricultural and biological sciencesGeneral biochemistry,genetics and molecular biologyGeneral medicineGeociênciasGeografíaHistoriaHistory & philosophy of scienceHuman geography and urban studiesInterdisciplinarInterdisciplinary research in the social sciencesLetras / linguísticaLinguística e literaturaMatemática / probabilidade e estatísticaMateriaisMedicina iMedicina iiMedicina iiiMedicina veterinariaMedicine (miscellaneous)MultidisciplinaryMultidisciplinary sciencesNutriçãoOdontologíaPlanejamento urbano e regional / demografiaPsicologíaPsychologyQuímicaSaúde coletivaServiço socialSociologíaSociologyZootecnia / recursos pesqueiros

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal PLoS ONE due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2012, it was in position 7/56, thus managing to position itself as a Q1 (Primer Cuartil), in the category Multidisciplinary Sciences.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 1.27. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 3.86 (source consulted: FECYT Feb 2024)
  • Field Citation Ratio (FCR) from Dimensions: 5.1 (source consulted: Dimensions Jul 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-07-19, the following number of citations:

  • WoS: 57
  • Scopus: 59
  • Europe PMC: 41
  • Google Scholar: 83
  • Open Alex: 68

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-07-19:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 79.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 80 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.

Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (MARTINEZ GRANERO, FRANCISCO MANUEL) and Last Author (Martin M).

the author responsible for correspondence tasks has been MARTIN BASANTA, MARTA.