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Analysis of institutional authors

Ramasco, FernandoCorresponding Author

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September 20, 2024
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Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies

Publicated to:Journal Of Personalized Medicine. 14 (2): 176- - 2024-02-01 14(2), DOI: 10.3390/jpm14020176

Authors: Ramasco, Fernando; Nieves-Alonso, Jesus; Garcia-Villabona, Esther; Vallejo, Carmen; Kattan, Eduardo; Mendez, Rosa

Affiliations

Hosp Univ La Princesa, Dept Anaesthesiol & Surg Intens Care, Diego Leon 62, Madrid 28006, Spain - Author
Pontificia Univ Catolica Chile, Fac Med, Dept Med Intens Adulto, Marcoleta 367, Santiago 8320000, Chile - Author

Abstract

Sepsis and septic shock are associated with high mortality, with diagnosis and treatment remaining a challenge for clinicians. Their management classically encompasses hemodynamic resuscitation, antibiotic treatment, life support, and focus control; however, there are aspects that have changed. This narrative review highlights current and avant-garde methods of handling patients experiencing septic shock based on the experience of its authors and the best available evidence in a context of uncertainty. Following the first recommendation of the Surviving Sepsis Campaign guidelines, it is recommended that specific sepsis care performance improvement programs are implemented in hospitals, i.e., "Sepsis Code" programs, designed ad hoc, to achieve this goal. Regarding hemodynamics, the importance of perfusion and hemodynamic coherence stand out, which allow for the recognition of different phenotypes, determination of the ideal time for commencing vasopressor treatment, and the appropriate fluid therapy dosage. At present, this is not only important for the initial timing, but also for de-resuscitation, which involves the early weaning of support therapies, directed elimination of fluids, and fluid tolerance concept. Finally, regarding blood purification therapies, those aimed at eliminating endotoxins and cytokines are attractive in the early management of patients in septic shock.

Keywords

Acute kidney injuryAdsorption therapiesBlood purificationCardiac dysfunctionCritically-ill patientsCytokineDiastolic functionEndotoxinExpert recommendationsFluid toleranceHemodynamic coherenceHemodynamic monitorizatioHemodynamic monitorizationOxirisPolymyxin-b hemoperfusionPredict fluid responsivenessRenal replacement therapySepsisSepsis nutritionSepsis phenotypesSeptic shockSevere sepsisSimplified definitioVolume hemofiltration

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Journal Of Personalized Medicine due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2024 there are still no calculated indicators, but in 2023, it was in position 51/174, thus managing to position itself as a Q1 (Primer Cuartil), in the category Health Care Sciences & Services.

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-07-19:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 46.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 59 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 42.35.
  • The number of mentions on the social network X (formerly Twitter): 82 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.

Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Chile.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (RAMASCO RUEDA, FERNANDO) .

the author responsible for correspondence tasks has been RAMASCO RUEDA, FERNANDO.